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Journal of Research in Medical Sciences، جلد ۲۰، شماره ۷، صفحات ۰-۰
عنوان فارسی
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عنوان انگلیسی Effects of Blackberry (Morus nigra L.) Consumption on Serum Concentration of Lipoproteins, Apo A-I, Apo B and Hs – CRP and Blood Pressure in Dyslipidemic Patients
چکیده انگلیسی مقاله Background: This study investigated blackberry (Persian mulberry) effects on apo A-I, apo B, high-sensitivity-C-reactive protein (hs-CRP), and systolic blood pressure (SBP) and diastolic blood pressure (DBP) in dyslipidemic patients. Materials and Methods: In this 8-week randomized clinical trial, 72 dyslipidemic patients were randomly divided into two groups: Intervention (300 mL/day blackberry juice with pulp) and control group (usual diets). Before and after the intervention, fasting blood samples were taken from both groups and serum concentration of lipoprotein, apo A-I and apo B, serum lipids (total cholesterol, low-density lipoprotein, high-density lipoprotein [HDL], and triglyceride), hs-CRP were measured. Blood pressure before and after the study was measured with a mercury manometer. Results: At week 8 in the intervention group, apo A-I and HDL increased significantly ( P = 0.015, P = 0.001, respectively), apo B and hs-CRP decreased significantly ( P = 0.044, P = 0.04, respectively). Mean changes in apo A-I and HDL and apo B/apo A-I ratio were significant between the groups ( P = 0.005, P = 0.014, and P = 0.009, respectively). After 8 weeks, there was a significant difference between hs-CRP mean values ( P = 0.01) of the groups. At week 8, SBP decreased significantly ( P = 0.005) in the intervention group with no significant differences for SBP mean values between the groups. No significant changes were observed in other lipid parameters and DBP in the intervention group and between the groups. Conclusion: Blackberry consumption may exert beneficial effects on apolipoproteins, blood pressure, and inflammatory markers in individuals with lipid disorders.
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نویسندگان مقاله سحر کشتکار آقابابایی | sahar keshtkar aghababaee


محمدرضا وفا | mohammadreza vafa


شیدفر | farzad shidfar


عاطفه تهورگر | atefeh tahavorgar


محمودرضا گوهری | mahmoodreza gohari


داود کاتبی | davod katebi


ویدا محمدی | vida mohammadi


نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/10277
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Articles
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