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Journal of Research in Medical Sciences، جلد ۱۹، شماره ۵، صفحات ۰-۰
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عنوان انگلیسی Insulin and leptin levels in overweight and normal-weight Iranian adolescents: The childhood and adolescence surveillance and prevention of adult noncommunicable diseases III study
چکیده انگلیسی مقاله Background: In this study, we aim to compare insulin and leptin levels in adolescents with or without overweight and in those with or without abdominal obesity. Materials and Methods: This case-control study was conducted among 486 samples. We randomly selected 243 overweight and an equal number of normal-weight adolescents from among participants of the third survey of a national surveillance program entitled “Childhood and Adolescence Surveillance and PreventIon of Adult Non-communicable diseases study.” Serum insulin and leptin were compared between two groups and their correlation was determined with other variables. Results: The mean age and body mass index (BMI) of participants were 14.10 ± 2.82 years and 22.12 ± 6.49 kg/m2, respectively. Leptin and insulin levels were higher in overweight than in normal-weight adolescents (P < 0.05). Leptin level was higher in children with abdominal obesity than in their other counterparts (P < 0.001). Leptin level was correlated with age, fasting blood glucose, BMI, and insulin level. Conclusion: Insulin and leptin levels were higher among overweight and obese children, which may reflect insulin and leptin-resistance. Given the complications of excess weight from early life, prevention and controlling childhood obesity should be considered as a health priority.
کلیدواژه‌های انگلیسی مقاله Children, insulin, leptin, obesity, overweight
نویسندگان مقاله احسان بهرامی | ehsan bahrami


پریسا میرمقتدایی | parisa mirmoghtadaee


گلایول اردلان | gelayol ardalan


حمید زرکش اصفهانی زرکش اصفهانی | hamid zarkesh esfahani zarkesh esfahani


محمد حسن تاج الدینی | mohammad hassan tajadini


شقایق haghjouy جوانمرد | shaghayegh haghjouy javanmard


حنانه نجفی | hananeh najafi


رویا کلیشادی | roya kelishadi


نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/9939
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Articles
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