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Journal of Research in Medical Sciences، جلد ۲۰۱۴، شماره ۰۱، صفحات ۰-۰

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عنوان انگلیسی Cavernomas: Outcomes after Gamma-Knife Radiosurgery In Iran
چکیده انگلیسی مقاله Background: Treatment of cavernomas remains a challenge in surgically inaccessible regions. The purpose of this study was to evaluate outcomes after Gamma-knife surgery (GKS) for these patients. Materials and Methods: A retrospective review of 100 patients treated between 2003 and 2011 was conducted in order to evaluate hemorrhage rates, complications, radiation effects after GKS. Dosage at the tumor margin was stratified into two groups: those that received less than or equal 13 Gy; and those who received more than 13 Gy. The demographic and clinical characteristics of patients including age, gender and hemorrhage rates were extracted from care records. Results: The median age was 32.5 years (ranging from 5 to 79). 44% were female. The median follow-up time was 42.2 months (ranging from 24 to 90). The median volume of the lesions was 1050.0 mm3 (ranging from 112.0 to 4100.0) before GKS. A reduction of 27.5% in median size of cavernomas was achieved at the last follow- up. There was 12% treatment-related morbidity after GKS. The hemorrhage rate in the first 2 years after GKS was 4.1%, and 1.9% thereafter. There was no mortality due to GKS and 93 patients were alive at the last follow-up. The radiation-related complication developed with marginal dose 13 Gy. Conclusion: The GKS for cavernomas appears to be a safe and beneficial in carefully selected patients. Low-dose GKS may be effective for the management of CMs. Keywords: Cavernomas, outcomes, Gamma-knife radiosurgery, Iran
کلیدواژه‌های انگلیسی مقاله Cavernomas, outcomes, Gamma-knife radiosurgery, Iran

نویسندگان مقاله دکترپریسا عظیمی | parisa azimi
department of neurosurgery, shahid beheshti university of medical sciences

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)

دکتر سهراب شهزادی | sohrab shahzadi
department of neurosurgery, shahid beheshti university of medical sciences

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)

محمد علی بیطرف | mohammad ali bitaraf
department of neurosurgery, shahid beheshti university of medical sciences

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)

مازیار آذر | maziar azar
department of neurosurgery, shahid beheshti university of medical sciences

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)

مزدک علیخانی | mazdak alikhani
department of neurosurgery, shahid beheshti university of medical sciences

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)

دکتر علیرضا زالی | alireza zali
department of neurosurgery, shahid beheshti university of medical sciences

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)

دکتر سهراب صادقی | sohrab sadeghi
department of neurosurgery, shahid beheshti university of medical sciences

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)


نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/9740
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Articles
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