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Journal of Research in Medical Sciences، جلد ۱۸، شماره ۱۰، صفحات ۰-۰
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عنوان انگلیسی Biochemical and hematological findings of Khorasan veterans 23 years after sulfur mustard exposure
چکیده انگلیسی مقاله Background: Sulfur mustard (SM) is an incapacitating chemical warfare agent, which has been widely employed in particular regions including Iran. We investigated and reported delayed biochemical and hematological complications of SM in severely toxic Iranian veterans 23 years after exposure. Materials and Methods: Forty-two Iranian veterans, residents of Khorasan Razavi, poisoned by SM, and suffering from clinical complications were investigated. A total of 30 healthy male volunteers were also selected as a control group. Biochemical and hematological variables were measured for the case and control groups. Data were analyzed using a Student’s t-test by InStat software (GraphPad Inc., San Diego, CA) to determine significant differences between the data from the two groups. Results: The percentages of reticulocytes were significantly higher in patients (0.82 ± 0.04, P < 0.05). Total protein and albumin levels were significantly lower in veterans (total protein: 7.58 ± 0.07 g/dL, albumin: 4.97 ± 0.04 g/dL, P < 0.01). In addition, we observed a significant increase in serum cholesterol (226.74 ± 5.23 mg/dL, P < 0.01), triglyceride (173.53 ± 17.05 mg/dL, P < 0.05),and gamma-glutamyl transferase (GTT) activity of the patients (44.04 ± 3.35 IU/L, P < 0.05). Conclusion: Results showed that SM can cause long-term effects on some biochemical factors of veterans. As many of the functional tests of liver and kidney between two groups were statistically unchanged, it seems that the observed biochemical changes may be secondary to delayed respiratory complications of the patients.
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نویسندگان مقاله محمد رضا کرامتی | mohammad reza keramati


مهدی بلالی مود | mahdi balali mood


سید رضا موسوی | seyed reza mousavi


محمود صادقی | mahmood sadeghi


بامداد ریاحی زنجانی | bamdad riahi zanjani


نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/9538
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Articles
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