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Journal of Research in Medical Sciences، جلد ۱۸، شماره ۷، صفحات ۶۲۲-۰

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عنوان انگلیسی A significant response to sunitinib in a patient with anaplastic thyroid carcinoma
چکیده انگلیسی مقاله Normal 0 false false false EN-US X-NONE AR-SA Anaplastic thyroid cancer (ATC) is a rare disease with an incidence of less than three cases per million of habitants in western countries. ATC accounts for 1‑10% of all tumors derived from the thyroid gland. Classic chemotherapy approach based on platinum and anthracyclines regimens have been considered standard for the last decades. Novel multitarget agents have shown promising responses; however, no positive randomized clinical trials are available up to now. To our knowledge, the case we are presenting here is the first reported case showing clinical and visual activity using sunitinib as a salvage treatment in an ATC patient who was not fit to receive systemic chemotherapy treatment.
کلیدواژه‌های انگلیسی مقاله Anaplastic thyroid cancer, angiogenesis, sunitinib

نویسندگان مقاله enrique grande | enrique grande
department of medical oncology, ramã³n y cajal university hospital, madrid, spain


jaume capdevila | jaume capdevila
department of medical oncology, vall d’hebrã³n university hospital, barcelona, universidad autã³noma de barcelona, spain


خوان josã© dã ez | juan josã© dã ez
department of endocrinology, ramã³n y cajal university hospital, madrid, spain


federico longo | federico longo
department of medical oncology, ramã³n y cajal university hospital, madrid, spain


alfredo carrato | alfredo carrato
department of medical oncology, ramã³n y cajal university hospital, madrid, spain



نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/9313
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Case Reports
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