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Journal of Research in Medical Sciences، جلد ۱۸، شماره ۱، صفحات ۱-۰
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عنوان انگلیسی Comparison of long chain polyunsaturated fatty acid content in human milk in preterm and term deliveries and its correlation with mothers’ diet
چکیده انگلیسی مقاله Normal 0 false false false EN-US X-NONE AR-SA Background: Human milk (H-M) is a main food for infants, and phospholipids especially long chain polyunsaturated fatty acids (LCPUFA) play an essential role in the growth and brain development. This study was designed to evaluate the fatty acid composition in HM of mothers with preterm and full term newborns and to determine the relationships of dietary intake of docosahexaenoic acid (DHA) and arachidonic acid (A.A) of mothers and the content of these fatty acids in their milks. Methods: The A.A and DHA of H-M were determined by gas chromatography at the third day after birth from mothers of 59 term and 58 preterm infants. Mothers were selected from those who delivered in Shahid Beheshti hospital, a referral teaching hospital affiliated to Isfahan University of Medical Sciences, Isfahan, Iran. Dietary fat composition of mothers was examined by a food-frequency questionnaire. Total fat content, DHA and A.A of H-M were compared in both groups. The correlation of dietary DHA and A.A were determined with DHA and A.A of H-M in both groups. Results: We found that maternal age, body mass index (BMI) and self- reported food- frequency questionnaire did not differ in two groups. In preterm and term groups, the mean A.A (0.19 ± 0.10 mg/ml and 0.16 ± 0.09 mg/ml, respectively), DHA (0.10 ± 0.06 mg/ml and 0.08 ± 0.05 mg/ml, respectively), and total fat content (2.58 ± 2.16 g/dl and 2.06 ± 1.22 g/dl respectively) of HM of mothers with preterm neonates were non-significantly higher than in mothers with term neonates. The percentage of DHA in the HM fat of preterm and term groups (0.45 ± 0.16% and 0.45 ± 0.18%, respectively) and the percentage of A.A (0.85 ± 0.26% and 0.84 ± 0.20%, respectively) were comparable with worldwide standards. No correlations were documented between DHA and A.A intake and DHA and A.A content of HM in both groups. Conclusion: Although DHA and A.A content of HM in preterm group were higher than term group, but this differences were not significant. The percentage of DHA and A.A were acceptable in our region in the milk fat of mothers with term and preterm neonates.
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نویسندگان مقاله رامین ایرانپور | ramin iranpour
faculty of medicine and child growth and development research center, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

رویا کلیشادی | roya kelishadi
department of pediatrics, faculty of medicine and child growth and development research center, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

شراره بابایی | sharareh babaie
faculty of medicine and child growth and development research center, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

کیانوش خسروی | kianoush khosravi
department of food technology research, national nutrition and food technology research institute, shaheed beheshti medical university, tehran, iran


صنم فرجیان | sanam farajian
faculty of nutrition, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/8887
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Articles
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