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Journal of Research in Medical Sciences، جلد ۱۸، شماره ۱، صفحات ۲۷-۰
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عنوان انگلیسی Total antioxidant potential and essential trace metals in the breast milk and plasma of Nigerian human immunodeficiency virus‑infected lactating mothers
چکیده انگلیسی مقاله Normal 0 false false false EN-US X-NONE AR-SA Background: The effect of Human Immunodeficiency Virus (HIV) on the immune system is well documented however; its impact on the nutritional and immunological qualities of the breast milk is scarce. AIM: Levels of some essential trace metals, albumin and antioxidant status in the plasma and breast milk of Nigerian HIV-infected lactating mothers were determined. Methods: Essential trace metals and total antioxidant potential were measured using spectrophotometric method while albumin was measured using single radial immunodiffusion technique. Results: Only the mean plasma level of albumin in HIV infected lactating mothers (HIM) (9.39 ± 4.46 g/L) was significantly reduced when compared with HIV free lactating mothers (HFM) (26.18 ± 18.43 g/L, P = 0.000), others had no significant difference. The mean breast milk levels of total antioxidant potential (1776.82 ± 564.26 µmolTE/Lvs 2384.67 ± 679.00 µmolTE/L, P = 0.0000), Cu (67.68 ± 5.04 µg/dLvs 71.10 ± 5.45 µg/dL, P = 0.033) and Fe (66.21 ± 6.31 µg/dLvs 71.20 ± 6.48 µg/dL, P = 0.011) were significantly reduced in HIM compared with HFM. No significant differences were observed in other parameters. Conclusion: It could be concluded from this study that hypoalbuminemia is a feature of HIV-infected lactating mothers and that breast milk of HIM has low antioxidant capacity.
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نویسندگان مقاله sheu k rahamon | sheu k rahamon
immunology unit, department of chemical pathology, college of medicine, university of ibadan, ibadan, nigeria


ganiyu o arinola | ganiyu o arinola
immunology unit, department of chemical pathology, college of medicine, university of ibadan, ibadan, nigeria


موسی o akiibinu | moses o akiibinu
department of chemical pathology, olabisi onabanjo university, ago-iwoye, oyo state, nigeria
نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/8892
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Articles
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