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Journal of Research in Medical Sciences، جلد ۱۷، شماره ۱۲، صفحات ۰-۰
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عنوان انگلیسی Comparison of the effects of canola oil versus sunflower oil on the biochemical markers of bone metabolism in osteoporosis
چکیده انگلیسی مقاله Normal 0 false false false EN-US X-NONE AR-SA MicrosoftInternetExplorer4 Background: Recently, omega-3 fatty acids are in the center of attention for their potent anti-inflammatory effects. Osteoporosis as a chronic senile disease is associated with inflammation, and the role of inflammatory mediators has been demonstrated in the recent years. The beneficial effects of n-3 fatty acids on bone were proven in many animal studies, while to date, no conclusive data is available in human. The aim of this study was to evaluate the impact of n-3 fatty acids on bone biomarkers in osteoporotic women. Materials and Methods: Forty osteoporotic post-menopausal women were recruited in the study and randomized in receiving either 40 g canola oil or the same amount sunflower oil per day as their dietary oil for 3 months. Serum levels of osteocalcin, bone alkaline phosphatase (BALP), N telo peptide collagen (NTX) and 25- hydroxy vitamin D3 were measured at baseline and at the end of the third month in both groups. Results: In the canola oil group, BALP and NTX were increased after 3 months while osteocalcin decreased in both groups slightly; however, none of these changes were significant. In both groups, serum vitamin D3 was increased significantly; however, this change between groups was not significant. Conclusion: Canola oil did not affect bone formation and resorption significantly after 3 months consumption. Further investigations with longer follow up are recommended.
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نویسندگان مقاله محبوبه عظمتی | mahbobe azemati
from the national research institute and faculty of nutrition and food technology, tehran, iran


راهبه شاکرحسینی | rahebe shakerhosseini
from the national research institute and faculty of nutrition and food technology, tehran, iran


آزیتا hekmatdos | azita hekmatdos
from the national research institute and faculty of nutrition and food technology, tehran, iran


دکتر حمید علوی مجد | hamid alavi majd
from the national research institute and faculty of nutrition and food technology and departments of biostatistics, shahid beheshti university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)

دکتر مهدی هدایتی | mehdi hedayati
3 laboratory, shahid beheshti university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)

آناهیتا هوشیار راد | anahita houshiarrad
from the national research institute and faculty of nutrition and food technology, tehran, iran


مونا حسینی | mona hosseini
from the national research institute and faculty of nutrition and food technology, tehran, iran


محمد e طاهریان | mohammad e taherian
from the national research institute and faculty of nutrition and food technology, tehran, iran


محمد f نوروزی | mohammad f noroozi
from the national research institute and faculty of nutrition and food technology, tehran, iran


مریم رشیدی | maryam rashidi
from the national research institute and faculty of nutrition and food technology, tehran, iran


اکرم امرایی | akram amraie
from the national research institute and faculty of nutrition and food technology, tehran, iran
نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/8835
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Articles
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