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Journal of Research in Medical Sciences، جلد ۱۷، شماره ۱۰، صفحات ۰-۰
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عنوان انگلیسی Anesthetic effects of adding intrathecal neostigmine or magnesium sulphate to bupivacaine in patients under lower extremities surgeries
چکیده انگلیسی مقاله Normal 0 false false false EN-US X-NONE AR-SA Background: Regional anesthesia is widely used to perform different surgical procedures including those performed on the extremities . In this study, the anesthetic effects of adding intrathecal neostigmine or magnesium sulphate to bupivacaine in patients under lower extremities surgeries were assessed. Materials and Methods: In this double-blind randomized clinical trial, 90 patients, candidate for lower extremities surgeries in a training hospital, were recruited. The patients with ASA class I and II aging from 20 to 65 years between 2009 and 2010 were evaluated. The selected patients were randomly assigned to receive either bupivacaine alone (Group A, n=30), or bupivacaine plus magnesium sulphate 50% (Group B, n=30), or bupivacaine plus neostigmine (Group C, n=30). Then sensory and motor onset and complete block and the time of recovery were measured. Results: The sensory block onset time were 3.03±0.981 in group A, 3.90±2.71 in group B and 3.7±1.08 in group C and knee flexion time were not significantly different among the three groups ( P > 0.05), whereas the time to complete motor block was significantly longer in group C and motor recovery time were significantly different between groups ( P =0.001). Conclusions: According to the obtained results, it may be concluded that magnesium sulphate is a safe and effective adjuvant for increasing the onset time of motor block .
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نویسندگان مقاله سید حمید رضا فیض | seyed hamid reza faiz
assistant professor of anesthesiology and pain, tehran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

پوپک رحیم زاده | poupak rahimzadeh
assistant professor of anesthesiology and pain, tehran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

مژگان سخایی | mozhgan sakhaei
anesthesiologist


فرناد ایمانی | farnad imani
associate professor of anesthesiology and pain, tehran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

پویا درخشان | pooya derakhshan
assistant professor of anesthesiology, birjand university of medical sciences, birjand, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی بیرجند (Birjand university of medical sciences)

نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/8700
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Articles
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