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Journal of Research in Medical Sciences، جلد ۱۶، شماره ۱۱، صفحات ۰-۰
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Relationship between echocardiographic findings and laboratory serum biomarkers in patients with and without low cardiac output
چکیده انگلیسی مقاله Normal 0 false false false EN-US X-NONE FA BACKGROUND : Cardiac dysfunction is seen in many patients and could be evaluated with echocardiography and serum biomarkers. The aim of this study was evaluation of the relationship between echocardiographic findings and laboratory serum biomarkers in children with and without low cardiac output. METHODS : Thirty patients older than 1 month with and without low cardiac output were enrolled in this study. It composed of 13 patients with dilated cardiomyopathy (DCM), 7 with end stage renal disease (ESRD) and 10 who had a Fontan operation. Echocardiography was performed with emphasis on shortening fraction (SF) and ejection fraction (EF). Blood samples were collected for measurement of atrial natriuretic peptide (ANP), high sensitivity C-reactive protein (hs-CRP) and alkaline phosphatase (Alk-P). Both echocardiographic findings and laboratory data were compared with control levels in twenty-seven normal children. Pearson correlation and regression analysis were conducted to evaluate the aforementioned associations. RESULTS : The mean of ANP and hs-CRP in the case group was statistically higher than control group (p < 0.001). The mean of ANP and hs-CRP were different in all groups (p < 0.001). There was a reverse linear regression between the SF and ANP in the case group (r = -0.594, p < 0.001). CONCLUSIONS : Determination of the plasma ANP and hs-CRP level may be helpful for decisions related to early diagnosis of patient with low cardiac output. KEYWORDS : Ejection Fraction, Shortening Fraction, Atrial Natriuretic Peptide, High Sensitivity C-reactive Protein .
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله محمد رضا خلیلیان | mohammad reza khalilian
department of pediatrics, school of medicine, isfahan university of medical sciences, isfahan, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

محمد رضا صبری | mohammad reza sabri
professor, department of pediatrics, school of medicine, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

عبدالرسول نیک یار | abdolrasoul nikyar
professor, department of pediatrics, school of medicine, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

شقایق حقجو جوانمرد | shaghayegh haghjooy javanmard
department of physiology, school of medicine, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/7258
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Articles
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