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Journal of Research in Medical Sciences، جلد ۱۶، شماره ۱۱، صفحات ۰-۰
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عنوان انگلیسی Cognitive impairments in patients with intractable temporal lobe epilepsy
چکیده انگلیسی مقاله Normal 0 false false false EN-US X-NONE FA BACKGROUND : Cognitive impairment associated with temporal lobe epilepsy (TLE) has been recognized in multiple studies. We designed this study to find a specific cognitive profile in patients with TLE who were candidates for epilepsy surgery. We also sought to find if neuropsychological assessment could differentiate left TLE, right TLE and normal subjects. METHODS : The sample of this study consisted of 29 patients with right TLE, 31 with left TLE, and 32 subjects without history of seizure as controls. For all recruited patients and controls, demographic questionnaire, Wechsler Memory Scale-III (WMS-III) and Wechsler Adult Intelligence Scale-R (WAIS-R) were administered. Multivariate analysis of variance was carried out to reveal differences in memory and intelligence performance between the 3 groups. RESULTS : All of the mean scores of the WMS-III indexes were significantly higher in the control group in comparison with the right or the left TLE groups (p < 0.001). There were not any significant differences between mean scores of WMS-III indexes of the right and the left. The WAIS-R also showed significantly better mean scores of full scale intelligence quotient (FSIQ) and performance intelligence quotient (PIQ) in the control groups than both of the right and left TLE patients (p < 0.001). Although the verbal intelligence quotient (VIQ) mean scores were significantly different between the left TLE and the control group (p = 0.037), there were not any significant differences between the right TLE patients and the control group. CONCLUSIONS : These findings indicated that WMS-III and WAIS-R can differentiate patients with refractory temporal lobe epilepsy from normal subjects. However, the obtained cognitive profile could not differentiate between the right and the left TLE. KEY W ORDS : Temporal Lobe Epilepsy, Cognitive Impairment, Memory, Wechsler Memory Scale.
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نویسندگان مقاله ماهگل توکلی | mahgol tavakoli
assistant professor, department of psychology, school of educational sciences and psychology, the university of isfahan, isfahan, iran

سازمان اصلی تایید شده: دانشگاه اصفهان (Isfahan university)

مجید برکتین | majid barekatain
psychosomatic research center, isfahan university of medical of sciences, isfahan. iran.

سازمان اصلی تایید شده: دانشگاه اصفهان (Isfahan university)

حمید طاهر نشاط دوست | hamid taher neshatdoust
professor, department of psychology, school of educational sciences and psychology, the university of isfahan, isfahan, iran

سازمان اصلی تایید شده: دانشگاه اصفهان (Isfahan university)

حسین مولوی | hossein molavi
professor, department of psychology, school of educational sciences and psychology, the university of isfahan, isfahan, iran

سازمان اصلی تایید شده: دانشگاه اصفهان (Isfahan university)

رضا کرمی نوری | reza kormi nouri
associate professor, department of psychology, school of educational sciences and psychology, the university of tehran, tehran, iran and orebro university, orebro, sweden

سازمان اصلی تایید شده: دانشگاه تهران (Tehran university)

علیرضا مرادی | alireza moradi
professor, department of psychology, school of educational sciences and psychology, tarbiat moallem university, tehran, iran


جعفر مهوری | jafar mehvari
associate professor, department of neurology, school of medicine, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

محمد زارع | mohammad zare
associate professor, department of neurology, school of medicine, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/7412
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