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Journal of Research in Medical Sciences، جلد ۱۶، شماره ۱۱، صفحات ۰-۰

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عنوان انگلیسی Prevention of etomidate-related myoclonus in anesthetic induction by pretreatment with magnesium
چکیده انگلیسی مقاله Normal 0 false false false EN-US X-NONE FA BACKGROUND : Etomidate frequently leads to myoclonic jerks during anesthetic induction. This study aimed to detect if pretreatment with magnesium decreases myoclonus incidence. METHODS : A hundred ASA (the American Society of Anesthesiologists) I-II patients were included and randomized into 2 groups. Three minutes before etomidate induction of anesthesia (by 0.3 mg/kg intravenous etomidate) , Group M received 2.48 mmol (60 mg) intravenous magnesium sulphate and Group P received equal volume of intravenous saline. Myoclonus was evaluated as "present/absent". RESULTS : The rate of myoclonus was significantly lower in Group M than in Group P (p < 0.01). Hemodynamic parameters revealed no significant difference between the two groups. CONCLUSIONS : Low dose magnesium pretreatment before etomidate induction of anesthesia significantly reduces unwanted myoclonic jerks and also protects the hemodynamic stability. KEYWORDS : Etomidate, Myoclonus, Magnesium Sulphate
کلیدواژه‌های انگلیسی مقاله Etomidate, myoclonus, magnesium sulphate

نویسندگان مقاله bã¼lent un | bã¼lent un
department of anesthesiology and reanimation, school of medicine, osmangazi university, eskisehir, turkey


دیلک ceyhan | dilek ceyhan
associate professor, department of anesthesiology and reanimation, school of medicine, osmangazi university, eskisehir, turkey


birgul yelken | birgul yelken
professor, department of anesthesiology and reanimation, school of medicine, osmangazi university, eskisehir, turkey



نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/6783
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Short Communications
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