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Journal of Research in Medical Sciences، جلد ۱۶، شماره ۱۱، صفحات ۰-۰
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عنوان انگلیسی Combined portal, splenic and mesenteric venous thrombosis in inactive ulcerative colitis with heterozygous mutation in MTHFR gene: A rare case of thrombophilia
چکیده انگلیسی مقاله Normal 0 false false false EN-US X-NONE FA Thrombophilia is a rare but potentially catastrophic phenomenon occurring in patients having tendency of thrombosis. It may lead to serious complications. The etiology of thrombophilia is thought to be multifactorial and related to both acquired and inherited factors. Inflammatory bowel disease is an acquired cause of thrombophilia. Thromboembolic events are seen during inflammatory bowel disease, especially during the active period of the disease. In inflammatory bowel disease, thrombus formation in portal, splenic and mesenteric veins are not common. Besides, the association of genetic disorders related to metabolism of homocysteine with inflammatory bowel disease has been evidenced, especially in Crohn disease and rarely in ulcerative colitis. We present a rare case of ulcerative colitis in association with combined portal, splenic and mesenteric vein thrombosis. The patient was recently diagnosed with the disease which was in the inactive period. Interestingly, our patient was also heterozygous for the mutation in methylenetetrahydrofolate reductase (MTHFR) gene. KEYWORDS : Thrombophilia, Inflammatory Bowel Disease, Ulcerative Colitis, Portal Vein Trombosis, Mentery Vein Thrombosis, Splenic Vein Thrombosis, Methylenetetrahy Drofolate Reductase Gene.
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نویسندگان مقاله gul gursoy | gul gursoy
associate professor, department of internal medicine, ministry of health ankara education and research hospital, ankara, turkey


آحمت cimbek | ahmet cimbek
ministry of health ankara education and research hospital, ankara, turkey


یاشار acar | yasar acar
ministry of health ankara education and research hospital, ankara, turkey


birsen erol | birsen erol
ministry of health ankara education and research hospital, ankara, turkey


hayriye cankar دال | hayriye cankar dal
ministry of health ankara education and research hospital, ankara, turkey


nuray evrin | nuray evrin
ministry of health ankara education and research hospital, ankara, turkey


اصلی gungor | asli gungor
ministry of health ankara education and research hospital, ankara, turkey
نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/6884
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Case Reports
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