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Journal of Research in Medical Sciences، جلد ۱۶، شماره ۱۰، صفحات ۰-۰
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Relation of resistin levels with C-reactve protein, homocysteine and uric acid in smokers and non-smokers
چکیده انگلیسی مقاله 800x600 Normal 0 false false false EN-US X-NONE AR-SA MicrosoftInternetExplorer4 BACKGROUND : The association between C-reactive protein, homocysteine, uric acid levels and cardiovascular risk have been debated for decades. Resistin is a newly discovered adipocyte derived cytokine. Smoking besides its effect on atherosclerosis, is shown to alter adipocytokine levels. Bearing in mind, these complex relationship of resistin with smoking, C-reactive protein, homocysteine and uric acid, we planned to investigate the association of resistin and these cardiovascular risk factors in smoker and non-smoker subjects. METHODS : We conducted a cross-sectional randomized study including 52 smoking and 33 non-smoking men. After making comparisons of C-reactive protein, homocysteine, uric acid and resistin between the two groups, we classified the subjects according to their insulin resistance and body mass and made again the comparisons. RESULTS : Resistin levels were higher in smokers than in non-smokers (p< 0.001) and also in insulin resistant than in non-insulin resistant smokers (p< 0.05). Resistin levels were indifferent in non-smokers as insulin resistance was concerned and in smoker or non-smokers as body mass index was concerned. As all subjects were grouped based on homeostasis model assesment index and body mass index, neither C-reactive protein nor homocysteine and uric acid levels differred. CONCLUSIONS : We found that smoking may have influence on resistin levels and in smokers, insulin resistance is related to resistin levels, but in smoker and non-smokers body mass may not have any association with resistin. Resistin also may not have a role in C-reactive protein, homocysteine and uric acid levels both in smokers and non-smokers. KEYWORDS : CRP, Homocysteine, Uric Acid, Resistin, Smoking.
کلیدواژه‌های انگلیسی مقاله CRP, homocysteine, uric acid, resistin, smoking
نویسندگان مقاله onur esbah | onur esbah
department of internal medicine, ministry of health ankara education and research hospital, ankara, turkey


gul gursoy | gul gursoy
associate professor, department of internal medicine, ministry of health ankara education and research hospital, ankara, turkey


nazlä± gulsoy kä±rnap | nazlä± gulsoy kä±rnap
department of internal medicine, ministry of health ankara education and research hospital, ankara, turkey


hacer cetiner | hacer cetiner
department of internal medicine, ministry of health ankara education and research hospital, ankara, turkey


berrin demirbas | berrin demirbas
associate professor, departement of endocrinology, mesa hospital, ankara, turkey


yaåÿar acar | yaåÿar acar
department of internal medicine, ministry of health ankara education and research hospital, ankara, turkey


مرات بایرام | murat bayram
department of internal medicine, ministry of health ankara education and research hospital, ankara, turkey
نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/7031
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Articles
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