| چکیده انگلیسی مقاله |
Normal 0 false false false EN-US X-NONE X-NONE BACKGROUND : The Alberta Stroke Program Early Computerized Tomography Score (ASPECTS) was used to detect significant early ischemic changes on brain CT of acute stroke patients. We designed the modified ASPECTS and compared it to the above system based on the inter-rater reliability. METHODS : A cross-sectional validation study was conducted based on the inter-rater reliability. The CT images were chosen from the stroke data bank of Ghaem hospital, Mashhad in 2010. The inclusion criteria were the presence of middle cerebral artery territory infarction and performance of CT within 6 hours after stroke onset. Axial CT scans were performed on a third-generation CT scanner (Siemens, ARTX, Germany). Section thickness above posterior fossa was 10 mm (130 kV, 150 mAs). Films were made at window level of 35 HU. The brain CTs were scored by four independent radiologists based on the ASPECTS and modified ASPECTS. The readers were blind to clinical information except symptom side. Cochrane Q and Kappa tests served for statistical analysis. RESULTS : 24 CT scans were available and of sufficient quality. Difference in distribution of dichotomized ≤7 and >7 ASPECT scores between four raters was significant (Q=13.071, df=3, p=0.04). Distribution of dichotomized < 6 and ≥6 scores based on modified ASPECT system between 4 raters was not significantly different (Q=6.349, df=3, p=0.096). CONCLUSIONS : Modified ASPECT method is more reliable than ASPECTS in detecting major early ischemic changes in stroke patients candidated to tPA thrombolysis. KEYWORDS : Normal 0 false false false EN-US X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin-top:0in; mso-para-margin-right:0in; mso-para-margin-bottom:10.0pt; mso-para-margin-left:0in; line-height:115%; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman";} Computed Tomography, Cerebral Infarction, Thrombolysis, Inter-Rater Reliability |
| نویسندگان مقاله |
کاویان قندهاری | kavian ghandehari
professor of cerebrovascular disease, neuroscience research center, department of neurology, school of medicine, mashhad university of medical sciences, mashhad, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)
محمد رضا رضوانی | mohammad reza rezvani
mohammad reza rezvani, md, assistant professor, department of internal medicine, school of medicine, birjand university of medical sciences, birjand, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی بیرجند (Birjand university of medical sciences)
محمد تقی شاکری | mohammad taghi shakeri
associate professor, department of biostatistics, school of medicine, mashhad university of medical sciences, mashhad iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)
مهدی محمدی فرد | mahdi mohammadifard
assistant professor, department of radiology, school of medicine, birjand university of medical sciences, birjand, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی بیرجند (Birjand university of medical sciences)
علی رضا احسان بخش | ali reza ehsanbakhsh
assistant professor, department of radiology, school of medicine, birjand university of medical sciences, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی بیرجند (Birjand university of medical sciences)
مهیار محمدی فرد | mahyar mohammadifard
assistant professor, department of radiology, school of medicine, birjand university of medical sciences, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی بیرجند (Birjand university of medical sciences)
علی رضا میرغلامی | ali reza mirgholami
assistant professor, department of radiology, school of medicine, birjand university of medical sciences, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی بیرجند (Birjand university of medical sciences)
رضا بوستانی | reza boostani
assistant professor, department of neurology, school of medicine, mashhad university of medical sciences, mashhad, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)
کوثر قندهاری | kosar ghandehari
research fellow, school of medicine, mashhad university of medical sciences, mashad, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)
زهرا ایزدی مود | zahra izadi mood
research fellow, department of neuroscience, school of medicine, mashhad university of medical sciences, mashad, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)
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