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Journal of Research in Medical Sciences، جلد ۱۶، شماره ۷، صفحات ۰-۰
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Evaluating hemodynamic outcomes of different dosages of intravenous nitroglycerin after coronary artery bypass graft surgery
چکیده انگلیسی مقاله BACKGROUND: Hemodynamic deterioration is a common postoperative problem. Intravenous nitroglycerin (NTG) is used for prevention of this complication. Nitroglycerin has different doses and is primarily a vasodilator. Applying different doses of intravenous NTG can induce different effects on post-operative cardiac instability, so we aimed to investigate whether there was a difference need for administration of inotrope drugs in patients undergoing CABG as indicators of cardiac instability. METHODS: Sixty seven consecutive patients enrolled in this double-blind clinical trial performed in Shahid Rajaee hospital, Shahid Beheshti University of Medical Science, Tehran, Iran. RESULTS: The decrease in blood pressure and the need for administration of epinephrine was more prevalent in warming up period in all three groups. No need for administration of epinephrine was detected before and during anesthesia in groups receiving 100 and 150 µg/min intravenous nitroglycerin, but 6.6 percent (1 patient) of patients receiving 50 µg/min epinephrine, demonstrated a decrease in blood pressure which necessitated the use of epinephrine. CONCLUSIONS: It seemed that application of different doses of intravenous nitroglycerin did not exert a significant influence on cardiac instability and the need for use of inotrope drugs. KEYWORDS: Nitroglycerin, CABG, Epinephrine. BACKGROUND: Hemodynamic deterioration is a common postoperative problem. Intravenous nitroglycerin (NTG) is used for prevention of this complication. Nitroglycerin has different doses and is primarily a vasodilator. Applying different doses of intravenous NTG can induce different effects on post-operative cardiac instability, so we aimed to investigate whether there was a difference need for administration of inotrope drugs in patients undergoing CABG as indicators of cardiac instability. METHODS: Sixty seven consecutive patients enrolled in this double-blind clinical trial performed in Shahid Rajaee hospital, Shahid Beheshti University of Medical Science, Tehran, Iran. RESULTS: The decrease in blood pressure and the need for administration of epinephrine was more prevalent in warming up period in all three groups. No need for administration of epinephrine was detected before and during anesthesia in groups receiving 100 and 150 µg/min intravenous nitroglycerin, but 6.6 percent (1 patient) of patients receiving 50 µg/min epinephrine, demonstrated a decrease in blood pressure which necessitated the use of epinephrine. CONCLUSIONS: It seemed that application of different doses of intravenous nitroglycerin did not exert a significant influence on cardiac instability and the need for use of inotrope drugs. KEYWORDS: Nitroglycerin, CABG, Epinephrine.
کلیدواژه‌های انگلیسی مقاله nitroglycerin, CABG, epinephrine.
نویسندگان مقاله غلامرضا معصومی | gholamreza masoumi
assistant professor, department of cardiac anesthesiology, shahid rajaee hospital, isfahan university of medical science, isfahan, iran.

سازمان اصلی تایید شده: دانشگاه اصفهان (Isfahan university)

عوض hidarpour | evaz hidarpour
professor, department of cardiac anesthesiology, shahid rajaee hospital, tehran university of medical science, tehran, iran.

سازمان اصلی تایید شده: دانشگاه تهران (Tehran university)

علی صادق پور طبایی | ali sadeghpour tabae
assistant professor, department of cardiac surgery, shahid rajaee hospital, tehran university of medical science, tehran, iran.

سازمان اصلی تایید شده: دانشگاه تهران (Tehran university)

محسن ziayeefard | mohsen ziayeefard
assistant professor, department of anesthesiology, shahid rajaee hospital, tehran university of medical science, tehran, iran.

سازمان اصلی تایید شده: دانشگاه تهران (Tehran university)

آتوسا azarasa | atosa azarasa
assistant professor, department of cardiac anesthesiology, shahid rajaee hospital, ghazvin university of medical science, ghazvin, iran.


امین abneshahidi | amin abneshahidi
assistant professor, department of anesthesiology, sadi hospital, isfahan university of medical science, isfahan, iran.

سازمان اصلی تایید شده: دانشگاه اصفهان (Isfahan university)

صنم جاوید انباردان | sanam javid anbardan
medical student, tehran university of medical science, tehran, iran.

سازمان اصلی تایید شده: دانشگاه تهران (Tehran university)

پرویز کاشفی | parviz kashefi
asociated professor, department of anesthesiologyanesthesiology, azahra hospitalhospital,isfahan university of medical science, isfahan, iran.

سازمان اصلی تایید شده: دانشگاه اصفهان (Isfahan university)

نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/6859
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Articles
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