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Journal of Research in Medical Sciences، جلد ۱۶، شماره ۴، صفحات ۰-۰
عنوان فارسی
چکیده فارسی مقاله
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عنوان انگلیسی Influence of the timing of cardiac catheterization and amount of contrast media on acute renal failure after cardiac surgery
چکیده انگلیسی مقاله Normal 0 false false false EN-US X-NONE AR-SA MicrosoftInternetExplorer4 BACKGROUND: There is limited data about the influence of timing of cardiac surgery in relation to diagnostic angiography and/or the impact of the amount of contrast media used during angiography on the occurance of acute renal failure (ARF). Therefore, in the present study the effect of the time interval between diagnostic angiography and cardiac surgery and also the amount of contrast media used during the diagnostic procedure on the incidence of ARF after cardiac surgery was investigated. METHODS: Data of 1177 patients who underwent different types of cardiac surgeries after cardiac catheterization were prospectively examined. The influence of time interval between cardiac catheterization and surgery as well as the amount of contrast agent on postoperative ARF were assessed using multivariable logistic regression. RESULTS: The patients who progressed to ARF were more likely to have received a higher dose of contrast agent compared to the mean dose. However, the time interval between cardiac surgery and last catheterization was not significantly different between the patients with and without ARF (p = 0.05). Overall, postoperative peak creatinine was highest on day 0, then decreased and remained significantly unchanged after this period. Overall prevalence of acute renal failure during follow-up period had a changeable trend and had the highest rates in days 1 (53.57%) and 6 (52.17%) after surgery. Combined coronary bypass and valve surgery were the strongest predictor of postoperative ARF (OR = 4.976, CI = 1.613-15.355 and p = 0.002), followed by intra-aortic balloon pump insertion (OR = 6.890, CI = 1.482-32.032 and p = 0.009) and usage of higher doses of contrast media agent (OR = 1.446, CI = 1.033-2.025 and p = 0.031). CONCLUSIONS: Minimizing the amount of contrast agent has a potential role in reducing the incidence of postoperative ARF in patients undergoing cardiac surgery, but delaying cardiac surgery after exposure to these agents might not have this protective effect. KEYWORDS: Contrast media, Iodine compounds, Adverse effects, Acute renal failure, Cardiac surgery, Angiography, Coronary artery bypass grafting.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله محسن میرمحمد صادقی | mohsen mirmohammad sadeghi
assistant professor, department of cardiac surgery, school of medicine, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

مژگان قاری پور | mojgan gharipour
researcher in clinical biochemistry, isfahan cardiovascular research institute, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

پیمان نیلفروش | peiman nilforoush
physician, delasa heart center, sina heart center, isfahan, iran


حمید shamsolkotabi | hamid shamsolkotabi
assistant professor, department of cardiology, school of medicine isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

حمید میرمحمد صادقی | hamid mirmohammad sadeghi
assistant professor, department of pharmaceutical biotechnology, school of pharmacy, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

امجد کیانی | amjad kiani
cardiac anesthesiologist, delasa heart center, sina heart center, isfahan, iran


پویا میرمحمد صادقی | pouya mirmohammad sadeghi
general practitioner, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

نیلوفر فرهمند | niloufar farahmand
head nurse of icu of open heart surgery, delasa heart center, sina heart hospital isfahan, iran
نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/6797
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Articles
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