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Journal of Research in Medical Sciences، جلد ۱۶، شماره ۰۳، صفحات ۰-۰
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژههای فارسی مقاله |
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| عنوان انگلیسی |
Effects of eicosapentaenoic acid and vitamin C on glycemic indices, blood pressure, and serum lipids in type 2 diabetic Iranian males |
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| چکیده انگلیسی مقاله |
BACKGROUND: Eicosapentaenoic acid (EPA) is the principal ω-3 fatty acids in marine oils. Fasting blood sugar (FBS), HbA1c and some of the plasma lipids and lipoproteins has been negatively related to the intake of ω-3 fatty acids and ascorbic acid, in some studies. Therefore, the purpose of this study was to assess the effects of EPA and/or vitamin C on glycemic indices, blood pressure, and plasma lipids in type 2 diabetic Iranian males. METHODS: Sixty five men with type 2 diabetes were enrolled into the study between April 2 and June 27, 2008. Venous blood samples were obtained from all participants after 10 hours of fasting, at the baseline and after the intervention. Subjects received 500 mg EPA and/or 200 mg vitamin C and/or placebo depending on their groups. For eight weeks, 15 participants received EPA supplements with vitamin C (group 1), 16 took EPA supplements and vitamin C placebo (group 2), 17 took EPA placebo and vitamin C (group 3), and 17 received EPA placebo and vitamin C placebo (group 4), daily. RESULTS: There were significant decreases in FBS, HbA1C, LDL-C and TG in groups 1, 2, 3 and 4 (p < 0.01), but significant decreases in TC were shown only in groups 1, 2 and 3 (p < 0.01). There was a significant increase in HDL-C in all groups (p < 0.01). CONCLUSIONS: In summary, it is concluded that, eight weeks of taking EPA + vitamin C supplementation improved the plasma levels of cardiovascular markers but didn't reduce BP. KEYWORDS: Eicosapentaenoic Acid, Ascorbic Acid, Fasting, Blood Glucose, Hemoglobin A, Glycosylated, Lipids, Blood Pressure, Diabetes Mellitus. |
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| کلیدواژههای انگلیسی مقاله |
EPA, vitamin C, FBS, HbA1C, lipids, blood pressure, Diabetes |
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| نویسندگان مقاله |
محمد مهدی شکوری محمودآبادی | mohammad mehdi shakouri mahmoudabadi
department of nutrition and biochemistry, school of public health, institute of public health research, tehran university of medical sciences, tehran, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)
محمود جلالی | mahmoud djalali
department of nutrition and biochemistry, school of public health, institute of public health research, tehran university of medical sciences, tehran, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)
سید ابوالقاسم جزایری | seyed abolghassem djazayery
department of nutrition and biochemistry, school of public health, institute of public health research, tehran university of medical sciences, tehran, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)
سید علی کشاورز | seyed ali keshavarz
department of nutrition and biochemistry, school of public health, institute of public health research, tehran university of medical sciences, tehran, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)
محمد رضا اشراقیان | mohammad reza eshraghian
department of biostatistics and epidemiology, school of public health, institute of public health research, tehran university of medical sciences, tehran, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)
علی اکبر صبور یراقی | ali akbar saboor yaraghi
department of nutrition and biochemistry, school of public health, institute of public health research, tehran university of medical sciences, tehran, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)
غلامرضا عسکری | gholamreza askari
department of nutrition, school of health, isfahan university of medical sciences, isfahan, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)
رضا غیاثوند | reza ghiasvand
department of nutrition, school of health, isfahan university of medical sciences, isfahan, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)
مهناز زارعی | mahnaz zarei
department of nutrition and biochemistry, school of public health, institute of public health research, tehran university of medical sciences, tehran, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)
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| نشانی اینترنتی |
http://jrms.mui.ac.ir/index.php/jrms/article/view/5465 |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
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| نوع مقاله منتشر شده |
Original Articles |
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