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Journal of Research in Medical Sciences، جلد ۱۶، شماره ۰۳، صفحات ۰-۰
عنوان فارسی
چکیده فارسی مقاله
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عنوان انگلیسی Helicobacter pylori serum antibody titers in patients with cerebral non-cardio embolic ischemic stroke
چکیده انگلیسی مقاله BACKGROUND: Helicobacter pylori (H. Pylori) infection has been associated with atherosclerosis of coronary arteries but there is lack of data regarding possible association between chronic H. Pylori infection and cerebral non-cardioembolic ischemia. We evaluated H. Pylori Serum antibody titers in patients with cerebral non-cardio embolic ischemic stroke . METHODS: This was a cross-sectional study that was performed in AlZahra hospital, Isfahan, Iran. 96 patients with ischemic stroke were enrolled in this study. Control group were selected from healthy blood donors. IgG and IgA antibodies to H. Pylori were detected using a rapid enzyme linked immunosorbent assay. Quantitative variables and categorical variables were compared using t student and chi-square test . RESULTS: There were 21 cases of hypertension and 5 cases of diabetes mellitus among patients. Patients and controls were similar regarding serum IgA and IgG titers as well as positivity. There were 13 and 15 cases of positive IgA and 44 and 39 cases of positive IgG among patients and controls, respectively. Also, there were 7 and 9 cases of both positive IgA and IgG in among patients and controls, respectively. No differences were found between the two groups in IgA or IgG titers or positivity (p > 0.05). CONCLUSIONS: Patients with stroke are not different regarding either H. Pylori IgA or IgG positivity or the antibody titers. Comparing genetic typing of H.Pylori in patients with or without stroke and diagnosis of H. Pylori with more specific and sensitive tests such as stool antigen test are recommended.
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نویسندگان مقاله سید علی موسوی | seyed ali mousavi
department of neurology, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

بهروز عطایی | behrooz ataei
infectious diseases and tropical medicine research center, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

ایرج کریمی | iraj karimi
infectious diseases and tropical medicine research center, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

کامیار اشرفی | kamyar ashrafi
infectious diseases and tropical medicine research center, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/6562
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Articles
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