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Journal of Research in Medical Sciences، جلد ۱۶، شماره ۱، صفحات ۱۶-۰
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Prevalence of adverse drug reactions at a private tertiary care hospital in south India
چکیده انگلیسی مقاله Normal 0 false false false EN-US X-NONE AR-SA MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:Arial; mso-bidi-theme-font:minor-bidi;} BACKGROUND: Adverse Drug Reactions (ADRs) constitute an enormous burden for the society. The aim of the present study was to detect, document, assess and report the suspected ADRs and preparation of guidelines to minimize the incidence of ADRs. METHODS: A prospective-observational study was conducted in the Department of General Medicine of a tertiary care hospital for 12 months from April 2008 to March 2009. Detected and suspected ADRs were analyzed for causality, severity and preventability using appropriate validated scales and were reported. ADR alert card was prepared and given to patients. Therapeutic guidelines were prepared and given to the relevant departments. RESULTS: A total of 57 ADRs were detected, documented, assessed and reported during the study period the incidence was found to be 1.8%. Assessment of severity of the suspected ADRs revealed that 12% of suspected ADRs were severe and 49% of ADRs were moderate in severity. Causality assessment was done which revealed 63% of ADRs were possibly drug-related. The majority of patients who had suffered from ADRs were above 60 years (56%). Gastrointestinal system was most commonly affected (37%) and the drug class mostly associated with ADRs was antibiotics (23%). Preventability of ADRs was assessed; and the results revealed that 28% of ADRs were definitely preventable. CONCLUSIONS: Measures to improve detection and reporting of adverse drug reactions by all health care professionals is recommended to be undertaken, to ensure, and improve patient's safety. In this way, hospital/clinical pharmacists play the cornerstone role. KEYWORDS: Adverse Drug Reactions (ADR), Prevalence, India.
کلیدواژه‌های انگلیسی مقاله ADR, Pharmaceutical Care
نویسندگان مقاله shanmugam sriram | shanmugam sriram
department of pharmacy practice, college of pharmacy, sri ramakrishna institute of paramedical sciences, coimbatore


علی قاسمی | ali ghasemi
department of pharmacy practice, college of pharmacy, sri ramakrishna institute of paramedical sciences, coimbatore


rajeswari rajeswari | rajeswari rajeswari
department of pharmacy practice, college of pharmacy, sri ramakrishna institute of paramedical sciences, coimbatore


manjula devi „ | manjula devi „
department of pharmacy practice, college of pharmacy, sri ramakrishna institute of paramedical sciences, coimbatore


rajalingam balasubramanian | rajalingam balasubramanian
department of pharmacy practice, college of pharmacy, sri ramakrishna institute of paramedical sciences, coimbatore


thengungal kochupapy ravi | thengungal kochupapy ravi
department of pharmacy practice, college of pharmacy, sri ramakrishna institute of paramedical sciences, coimbatore


علی محمد سبزقبایی | ali mohammad sabzghabaee
director of the isfahan clinical toxicology research center, former director of the regulatory provincial adr committee, isfahan university of medical sciences, isfahan

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/4713
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Articles
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