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Journal of Research in Medical Sciences، جلد ۱۶، شماره ۱، صفحات ۶۸-۰
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عنوان انگلیسی Low dose levobupivacaıne 0.5% with fentanyl in spinal anaesthesia for transurethral resection of prostate surgery
چکیده انگلیسی مقاله Normal 0 false false false EN-US X-NONE AR-SA MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:Arial; mso-bidi-theme-font:minor-bidi;} BACKGROUND: Levobupivacaine 0.5% and bupivacaine 0.5% were shown to be equally effective in spinal anaesthesia. In previous studies, low dose bupivacaine with an intrathecal opioid was used successfully in urological surgery. The aim of this study was to evaluate the clinical effectiveness and block quality of low dose levobupivacaine, and compare it with low dose bupivacaine when they are combined with fentanyl in transurethral resection of prostate surgery. METHODS: Forty nine patients undergoing transurethral prostate surgery were enrolled in this prospective, randomized and double blind study. Patients in levobupivacaine group received 5 mg levobupivacaine + 25 µg fentanyl and bupivacaine group received 5 mg bupivacaine + 25 µg fentanyl. Demographic data, surgery times, hemodynamic parameters, block qualities and patient and surgeon satisfactions were recorded. RESULTS: Demographic data, surgery times and patient and surgeon satisfactions were similar in both groups. Hemodynamic parameters were comparable and stable during the procedure in both groups. Sensory block characteristics were comparable and clinically effective in both groups. While 3 patients in bupivacaine group had Bromage score of 3 at the beginning of the surgery, no patient in levobupivacaine group had this score and this difference was significant (p = 0.042). Bromage scores at the end of the surgery were comparable in both groups. CONCLUSIONS: In conclusion, for transurethral prostate surgery 5 mg levobupivacaine with 25 µg fentanyl can provide stable hemodynamic profile, patient and surgeon satisfaction and effective sensorial blockade with less motor blockade in spinal anaesthesia; so it could be used at low doses as a good alternative to bupivacaine. KEYWORDS: Levobupivacaine, Bupivacaine, Fentanyl, Anaesthesia, Spinal, Transurethral Resection of Prostate.
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نویسندگان مقاله erkan yavuz akcaboy | erkan yavuz akcaboy
ankara numune research and training hospital, department of anesthesiology and reanimation, ankara


zeynep نور akcaboy | zeynep nur akcaboy
ankara numune research and training hospital, department of anesthesiology and reanimation, ankara


nermin gogus | nermin gogus
assisstant professor, ankara numune research and training hospital, department of anesthesiology and reanimation, ankara
نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/5518
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