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Journal of Research in Medical Sciences، جلد ۱۴، شماره ۶، صفحات ۳۴۹-۰
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عنوان انگلیسی Associates of poor physical and mental health-related quality of life in beta thalassemia-major/intermedia
چکیده انگلیسی مقاله BACKGROUND : Using two logistic regression models, we determined the associates of poor physical and mental health related quality of life (HRQoL) among beta thalassemia patients. METHODS : In this cross-sectional study which was conducted during 2006 and 2007 in outpatient adult thalassemia clinic, Blood Transfusion Organization, Tehran, Iran, Short Form 36 (SF-36) was used for measuring HRQoL in 179 patients with beta thalassemia (major/intermedia). We determined scores higher than third quartiles of obtained PCS and MCS scores as the cutoff points of good HRQoL. Poor HRQoL was defined scores lower than first quartiles of obtained PCS and MCS scores. Two distinct logistic regression models were used to derive associated variables including demographic, clinical, and psychological factors. RESULTS : The regression models suggested that poor physical HRQoL was positively associated with somatic comorbidities (OR = 1.472, CI = 1.021-2.197, p = 0.048) and depression score (OR = 8.568, CI = 2.325-31.573, p = 0.001). The variables that were associated with poor mental HRQoL were anxiety score (OR = 9.409, CI = 1.022-89.194, p = 0.049) and depression score (OR = 20.813, CI = 4.320-100.266, p < 0.001). CONCLUSIONS : Depression is associated with both poor physical and mental HRQoL among patients with major/intermedia beta thalassemia, however somatic comorbidities and anxiety are associated with poor physical and mental HRQoL, respectively. KEYWORDS : Thalassemia, Health Related Quality of Life, Anxiety, Depression, Somatic Comorbidities. Normal 0 false false false MicrosoftInternetExplorer4
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نویسندگان مقاله آزیتا آذرکیوان | azita azarkeyvan
blood transfusion research center, tehran blood transfusion organization, tehran, iran

سازمان اصلی تایید شده: سازمان انتقال خون ایران (Blood transfusion research center)

بشیر حاجی بیگی | bashir hajibeigi


مریم مغانی لنکرانی | maryam moghani lankarani


مهشید نامداری | mahshid namdari


شروین assaric | shervin assaric
medicine and health promotion institute, tehran, iran
نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/2876
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Articles
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