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Journal of Research in Medical Sciences، جلد ۱۱، شماره ۵، صفحات ۲۹۲-۰
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عنوان انگلیسی The comparison between suppository diclofenac and pethidine in post-cesarean section pain relief: a randomized controlled clinical trial
چکیده انگلیسی مقاله BACKGROUND: Narcotic drugs are usually used for postoperative pain control which could cause several complications such as respiratory depression and apnea. Therefore, replacement of these drugs with safer analgesics is recommended. The aim of this study was to compare the analgesic effects of suppository diclofenac and pethidine in post-cesarean section (C/S) patients. METHODS: In this clinical trial, pregnant women who were admitted to Alzahrah Hospital, Isfahan, Iran, between August and February 2004 and met the inclusion criteria were recruited. After obtaining informed consent, the patients were randomly assigned (block randomization) to two groups. In group A, 100 mg rectal suppository diclofenac was used after operation at four time points: at the end of operation and 8, 16 and 24 hours after the operation. Group B received pethidine 1 mg/kg intramuscularly at similar time points. The pain scores were assessed at 2, 10, 18 and 26 hours after C/S using the Visual Analogue Scale (VAS). Age, gestational age, parity, history of previous abortion, C/S and abdominal surgery, level of education, pain score, side effects and satisfaction level were assessed. Analysis was carried out with ANCOVA model and χ2 Mantel Haenszel tests by SPSS.10 software. P 0.05). There was no significant difference between side effects in the two groups except for dizziness in 11 cases in group B. There were significant statistical difference between pain intensity in 10, 18 and 26 hours after C/S in group A and group B (2.05 ± 2.07, 1.4 ± 1.6 and 0.5 ± 1.1 vs. 2.6 ± 2.2, 2.3 ± 2.2 and 1.3 ± 1.9) respectively. CONCLUSIONS: The results of the present study showed that the use of suppository diclofenac is an appropriate replacement therapy for pain relief after C/S. KEY WORDS: Diclofenac, pethidine, cesarean section, pain relief.
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نویسندگان مقاله زیبا ظهیری سروری | ziba zahiri soroori
department of obstetic and gynecology, gilan university of medical sciences

سازمان اصلی تایید شده: دانشگاه گیلان (Guilan university)

سیده هاجر شارمی | seyedeh hajar sharami
department of obstetic and gynecology, gilan university of medical sciences

سازمان اصلی تایید شده: دانشگاه گیلان (Guilan university)

آبتین حیدرزاده | abtin heidarzadeh
department of epidemiology, gilan university of medical sciences

سازمان اصلی تایید شده: دانشگاه گیلان (Guilan university)

لیلا شکری | leila shokri
department of epidemiology, gilan university of medical sciences

سازمان اصلی تایید شده: دانشگاه گیلان (Guilan university)

نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/510
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Articles
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