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International Journal of Organ Transplantation Medicine، جلد ۱، شماره ۲، صفحات ۰-۰

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عنوان انگلیسی The Impact of Hepatitis B Infection on Outcome of Kidney Transplantation: A Long-Term Study
چکیده انگلیسی مقاله Background: With the success of kidney transplantation, liver disease has emerged as an important cause of morbidity and mortality in kidney recipients. Objective: To determine the impact of hepatitis B virus (HBV) infection on patients and graft survival in both short- and long-terms. Methods: 99 renal transplant patients infected with HBV on follow-up in two major transplant centers were included in a retrospective study. These patients were grafted between 1986 and 2005 and divided into two groups: (1) those only positive for hepatitis B surface antigen (HBsAg) and (2) those who were also positive for hepatitis C virus antibodies (HCV Ab). Results: There were 88 patients with HBsAg + and 11 with both HBsAg + and HCV Ab + . The mean±SD age of patients was 38.8±13.2 years, and the median follow-up after transplantation was 19 months. Although not significant, the allograft survival rate in the first group (HBV + ) was better compared to that in the second group (HBV + and HCV + ); 1, 5 and 10 years graft survival rates were 91, 77 and 62 in the first group and 70, 56 and 28 in the second group, respectively (P=0.07). The overall mortality was 5% (4 of 88) in the first and 27% (3 of 11) in the second group (P=0.02). Conclusion: Renal allograft recipients with HBV and HCV infections has a poor survival rate compared to patients with only HBV infection. However, there is no significant difference in terms of renal graft survival between the two groups.
کلیدواژه‌های انگلیسی مقاله Kidney transplantation,Hepatitis B virus,Hepatitis C virus

نویسندگان مقاله b عین اللهی | b einollahi


سید محمد علویان | s m alavian


m دکتر محبوب لسان پزشکی | m lessan pezeshki


n سیم فروش | n simforoosh


محمدحسین نوربالا | m h nourbala


z رستمی | z rostami


v وحید | v pourfarziani


e نعمتی | e nemati


m شرفی | m sharafi


m نفر | m nafar


f پور رضا قلی | f pour reza gholi


a فیروزان | a firoozan



نشانی اینترنتی http://www.ijotm.com/ojs/index.php/IJOTM/article/view/28
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نوع مقاله منتشر شده Original Articles
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