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Iranian Journal of Neonatology، جلد ۶، شماره ۱، صفحات ۸-۱۲
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عنوان انگلیسی Prevalence of serum antibodies to TORCH infection in the first trimester of the pregnancy in Kashan, Iran
چکیده انگلیسی مقاله Introduction:TORCH infections causing via Toxoplasma gondii, other microorganisms (e.g., Treponema pallidum), Rubella virus, Cytomegalovirus (CMV) and the Herpes Simplex Virus (HSV) types 1 and 2 during the first trimester of pregnancy can lead to severe fetal anomalies or even fetal loss. The current study determined the serological data of TORCH infections in women who were in their first trimesters of pregnancy.This descriptive study was carried out on 80 pregnant women in their first trimester in Kashan, Iran.Methods: To detect specific IgM antibodies and specific IgG antibodies against the TORCH infections via ELISA, Sera were collected from the pregnant women.Results: The specific IgG antibodies were found to be positive in 30(37.5%) cases for toxoplasmosis, in 74 (92.5%) cases for the Rubella virus, in 79(98.8%) cases for CMV and in 73 samples (91.3%) for the HSV types 1 and 2 infection. 3.8% of cases were found to be seropositive for Toxoplasma IgM antibody (95% CI, 0.38-7.9), 5% were positive for CMV IgM antibody (95% CI, 0.23-9.77) and 7.5% were positive for the HSV IgM antibody (95% CI, 1.8-13.2). 63.8% of pregnant women were at risk for at least to one of the TORCH agents.Conclusion: This study showed a high prevalence of infections caused by TORCH agents among pregnant women. Therefore, national screening programmed is necessary to screen the TORCH infections routinely and to prevent and treat congenital TORCH infection
کلیدواژه‌های انگلیسی مقاله TORCH, IgM, IgG, Antibodies, Pregnant
نویسندگان مقاله ساره باقری جوشقانی | sareh bagheri josheghani
department of microbiology and immunology, faculty of medicine, kashan university of medical sciences, kashan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی کاشان (Kashan university of medical sciences)

رضوان منیری | rezvan moniri
department of microbiology and immunology, faculty of medicine, kashan university of medical sciences, kashan, iran; anatomical sciences research center, kashan university of medical sciences, kashan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی کاشان (Kashan university of medical sciences)

فاطمه باغبانی طاهری | fatemeh baghbani taheri
refrence labratory, kashan university of medical sciences, kashan, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی کاشان (Kashan university of medical sciences)

سمانه سادات | samaneh sadat
paramedicine college, kashan university of medical sciences

سازمان اصلی تایید شده: دانشگاه علوم پزشکی کاشان (Kashan university of medical sciences)

زهرا حیدرزاده | zahra heidarzadeh
refrence labratory, kashan university of medical sciences, kashan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی کاشان (Kashan university of medical sciences)

نشانی اینترنتی http://ijn.mums.ac.ir/article_4149.html
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