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Avicenna Journal of Phytomedicine، جلد ۶، شماره ۳، صفحات ۲۸۴-۲۹۴
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عنوان انگلیسی Anti-inflammatory and antinociceptive activities of Solenostemon monostachyus aerial part extract in mice
چکیده انگلیسی مقاله Objective: Solenostemon monostachyus is used in traditional medicine for the treatment of various ailments such as ulcer, hypertension, pains and inflammatory diseases. Evaluation of anti-inflammatory and analgesic activities of S. monostachyus aerial parts was carried out to ascertain its uses in traditional medicine. Materials and Methods: The aerial parts of S. monostachyus was cold extracted by soaking the dried powdered material in ethanol. The aerial parts crude extract (75 –225 mg/kg) of S. monostachyus was investigated for analgesic and anti-inflammatory activities using various experimental models; acetic acid, formalin and thermal- induced pains models for analgesic study and carrageenin, egg albumin and xylene – induced edema models for anti-inflammatory investigation. Results: The extract caused a significant (pConclusion: The anti-inflammatory and analgesic effects of this plant may in part be mediated through the chemical constituents of the plant and the results of the analgesic action suggest central and peripheral mechanisms. The findings of this work confirm the ethno medical use of this plant to treat inflammatory conditions.
کلیدواژه‌های انگلیسی مقاله Solenostemon monostachyus, Antiinflammatory, Analgesic
نویسندگان مقاله jude fiom okokon | jude fiom okokon
department of pharmacology and toxicology, faculty of pharmacy, university of uyo, uyo, nigeria


koofreh دیویس | koofreh davis
department of physiology, faculty of basic medical sciences, university of uyo, uyo, nigeria


lucky legbosi nwidu | lucky legbosi nwidu
department of pharmacology and toxicology, faculty of pharmacy, niger delta university, wilberforce island, bayelsa state
نشانی اینترنتی http://ajp.mums.ac.ir/article_5485.html
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Research Article
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