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Avicenna Journal of Phytomedicine، جلد ۴، شماره ۶، صفحات ۳۷۱-۳۷۶
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی The effects of Artemisia deserti ethanolic extract on pathology and function of rat kidney
چکیده انگلیسی مقاله Objectives: Medicinal plants played an important role in human health. The kidney is a major organ for elimination the additional materials of body. Some of metabolic waste products are excreted through the kidneys, give us useful information about kidney health. Therefore, the aim of this research was to study the effects of A. deserti flowering tips extract on kidney. Materials and Methods: Three groups of animal were studied. Wistar rats were divided into three groups. Group 1 was injected with saline, group 2 and 3 were injected with extract, 100 mg/kg and 200 mg/kg, respectively. The animals were anesthetized, blood samples were collected 2 days after the last injection, then urea, uric acid and creatinine levels were assayed. Also, the kidney histology was studied. Results: No significant changes in urea and uric acid were observed. But, creatinine concentration was changed significantly in group 3 compared to other groups. The extract caused histologic changes in the kidney, including, glomerular atrophy, congestion of inflammatory cells and degeneration of the renal tubules. Conclusion: The results showed that A. deserti extract was able to damage the kidney tissue. However, the reason for these histopathological changes remains to be clarified.
کلیدواژه‌های انگلیسی مقاله Artemisia deserti, Extract, kidney, Rat
نویسندگان مقاله علی نوری | ali noori
department of biology, falavarjan branch, islamic azad university, isfahan, i.r. iran

سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)

لیلا امجد | leila amjad
department of biology, falavarjan branch, islamic azad university, isfahan, i.r. iran

سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)

فرشته یزدانی | fereshteh yazdani
young researchers and elite club, falavarjan branch, islamic azad university, isfahan, i.r. iran

سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)

نشانی اینترنتی http://ajp.mums.ac.ir/article_3259.html
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Short communication
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