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Avicenna Journal of Phytomedicine، جلد ۳، شماره ۴، صفحات ۳۱۳-۳۲۰
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عنوان انگلیسی Characterization of phytoconstituents and evaluation of total phenolic content, anthelmintic, and antimicrobial activities of Solanum violaceum Ortega. (Family:Solanaceae)
چکیده انگلیسی مقاله Objective: The present study was conducted to detect possible chemicals (phytoconstituents), prove ethno-medicinal value of the plant, and investigate antimicrobial, anthelmintic, and total phenolic content of crude methanolic extract of the Solanum violaceum plant. Materials and Methods: Phytochemical screening was carried out using different chemical group test methods. In anthelmintic activity test (using Pheretima posthuma model), five concentrations (10, 20, 30, 40, 50, and 80 mg/ml in distilled water) of extracts and albendazole as standard were used which involved the vermifuge and vermicidal activity on the worms. For the evaluation of in vitro antimicrobial activity, disc diffusion method, and to determine the total phenolic content, Folin-Ceocalteu method (gallic acid as standard) were used. Results: The phytoconstituent analysis revealed presence of alkaloids, carbohydrate, glycoside, flavonoid, saponin, gum, diterpenes, phenol, protein, and tannin. The crude extract exhibited significant anthelmintic property comparing with the standard. The methanolic extract revealed broad-spectrum antimicrobial activity at the concentration of 400 µg/disc. The results were compared with that of the standard ciprofloxacin. The extract exhibited moderate amount of total phenolic compound (54.67±1.18 mg/gm of gallic acid equivalent). Conclusion: Since S. violaceum have shown antimicrobial, antioxidant, and anthelmintic activities, more studies such as anti-inflammatory, analgesic, antipyretic, and other pharmacological activities should be carried out to justify its traditional use, as the plant is available and used broadly in the rural areas for folkloric remedies. 
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نویسندگان مقاله غلام sarwar raju | golam sarwar raju
department of pharmacy, noakhali science and technology university, sonapur, noakhali- 3814 bangladesh


md میزانور رحمان مغال | md mizanur rahman moghal
department of pharmacy, noakhali science and technology university, sonapur, noakhali- 3814, bangladesh


سید masudur رحمان dewan | syed masudur rahman dewan
department of pharmacy, noakhali science and technology university, sonapur, noakhali- 3814 bangladesh


محمد nurul امین | mohammad nurul amin
department of pharmacy, noakhali science and technology university, sonapur, noakhali- 3814 bangladesh


md mustahsan billah | md mustahsan billah
department of pharmacy, noakhali science and technology university, sonapur, noakhali- 3814 bangladesh
نشانی اینترنتی http://ajp.mums.ac.ir/article_1056.html
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Research Article
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