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World Journal of Plastic Surgery، جلد ۴، شماره ۱، صفحات ۶۶-۷۳

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عنوان انگلیسی The Healing Effects of Aquatic Activities and Allogenic Injection of Platelet-Rich Plasma (PRP) on Injuries of Achilles Tendon in Experimental Rat
چکیده انگلیسی مقاله BACKGROUND Clinical tendon injuries represent serious and unresolved issues of the case on how the injured tendons could be improved based on natural structure and mechanical strength. The aim of this studies the effect of aquatic activities and alogenic platelet rich plasma (PRP) injection in healing Achilles tendons of rats. METHODS Forty rats were randomly divided into 5 equal groups. Seventy two hours after a crush lesion on Achilles tendon, group 1 underwent aquatic activity for 8 weeks (five sessions per week), group 2 received intra-articular PRP (1 ml), group 3 had aquatic activity together with injection PRP injection after an experimental tendon injury, group 4 did not receive any treatment after tendon injury and the control group with no tendon injuries. of 32 rats. After 8 weeks, the animals were sacrificed and the tendons were transferred in 10% formalin for histological evaluation. RESULTS There was a significant increase in number of fibroblast and cellular density, and collagen deposition in group 3 comparing to other groups denoting to an effective healing in injured tendons. However, there was no significant difference among the studied groups based on their tendons diameter. CONCLUSION Based on our findings on the number of fibroblast, cellular density, collagen deposition, and tendon diameter, it was shown that aquatic activity together with PRP injection was the therapeutic measure of choice enhance healing in tendon injuries that can open a window in treatment of damages to tendons.
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نویسندگان مقاله حمید رجبی | hamid rajabi
department of exercise physiology, faculty of physical education and sport sciences, kharazmei university, tehran, iran


هما شیخانی شاهین | homa sheikhani shahin
department of exercise physiology, faculty of physical education and sport sciences, kharazmei university, tehran, iran


منیژه نوروزیان | manijeh norouzian
department of exercise physiology, faculty of physical education and sport sciences, kharazmei university, tehran, iran


داود مهربانی | davood mehrabani
stem cell and transgenic technology research center, department of pathology, shiraz university of medical sciences, shiraz, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شیراز (Shiraz university of medical sciences)

سیف الله دهقانی ناژوانی | seifollah dehghani nazhvani
department of veterinary surgery, school of veterinary medicine, shiraz university, shiraz, iran

سازمان اصلی تایید شده: دانشگاه شیراز (Shiraz university)


نشانی اینترنتی http://www.wjps.ir/browse.php?a_code=A-10-1-48&slc_lang=en&sid=en
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