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Nanomedicine Journal، جلد ۳، شماره ۱، صفحات ۶۵-۶۸
عنوان فارسی
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عنوان انگلیسی Investigation of the effect of different parameters on the phase inversion temperature O/W nanoemulsions
چکیده انگلیسی مقاله Objective(s): Nanoemulsions are a kind of emulsions that can be transparent, translucent (size range 50-200 nm) or "milky" (up to 500 nm). Nanoemulsions are adequatly effective for transfer of active component through skin which facilitate the entrance of the active component . The transparent nature of the system and lack of the thickener and fluidity are among advantages of nanoemulsion. Materials and Methods: In this study, a nanoemulsion of lemon oil in water was prepared by the phase inversion temperature (PIT) emulsification method in which the tween 40 was used as surfactant. The effect of concentration of NaCl in aqueous phase, pH and weight percent of surfactant and aqueous on the PIT and droplet size were investigated. Results: The results showed that with increasing of concentration of NaCl from 0.05 M to 1 M, PIT decrease from 72 to 50. The average droplet sizes, for 0.1, 0.5 and 1 M of NaCl in 25 ºC are 497.3, 308.1 and 189.9 nm, respectively and the polydispersity indexes are 0.348, 0.334 and 0.307, respectively. Conclusion: Considering the characteristics of nanoemulsions such as being transparent, endurance of solution and droplet size can provide suitable reaction environment for polymerization process used in making hygienic and medical materials.
کلیدواژه‌های انگلیسی مقاله Nanoemulsion, Phase inversion temperature, Surfactant
نویسندگان مقاله d کاویانی | d. kaviani
young researchers and elite club, east tehran branch, islamic azad university, tehran, iran

سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)

m کونانی | m. koonani
department of chemistry, faculty of science, arak branch, islamic azad university, arak, iran

سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)

m ساقی | m. saghi
department of chemistry, faculty of science, arak branch, islamic azad university, arak, iran

سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)

m حسین بیگتن | m hosein bigtan
department of chemistry, faculty of science, arak branch, islamic azad university, arak, iran

سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)

نشانی اینترنتی http://nmj.mums.ac.ir/article_6198.html
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