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Asia Pacific Journal of Medical Toxicology، جلد ۴، شماره ۱، صفحات ۵۱-۵۴
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عنوان انگلیسی Rapid Death Due to Alcohol Withdrawal Syndrome: Case Report and Review of Literature
چکیده انگلیسی مقاله Background: Alcohol withdrawal syndrome (AWS) is one of the most serious complications associated with chronic alcoholism. Sudden deaths are not uncommon in AWS. In severe stages of AWS, delirium tremens (DT) occurs, which is characterized with agitation, global confusion, disorientation, visual and auditory hallucinations in addition to autonomic hyperactivity. Case report: A 30-year old man, chronic and heavy alcohol drinker for 10 years, abstained from alcohol for 3 days. Consequently, he started having palpitations, sweating and tremors. A day later, he was found having hallucinations and delirium. The patient was immediately transferred to the hospital. On admission, he was stuporous and had difficulty in breathing. He developed generalized seizures later on. He was successfully intubated, but there was bleeding through it. The patient's condition deteriorated very rapidly and he died within two hours. After death, his body was transferred to forensic department. In autopsy, gastrointestinal tract was found to be intact. Massive pulmonary hemorrhage was present on cut section. Liver was found to be with yellowish discoloration and early cirrhotic changes. In heart, left ventricular hypertrophy with narrowed lumen was present and coronary arteries were patent. Discussion: Alcoholism is associated with liver dysfunction and especially in final phases with cirrhosis. Hence and due to resultant coagulopathy, patients are vulnerable to internal bleedings. Hypertrophic cardiomyopathy also occurs in chronic alcoholics. Therefore, we can speculate that our patient developed pulmonary hemorrhage as a result of combined effect of coagulopathy secondary to cirrhosis, alveolar damage (seizure and artificial ventilation) and congestive heart failure. Conclusion: For a patient with delirium, convulsions, respiratory distress and coagulopathy, diagnosis of DT should be kept in mind.
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نویسندگان مقاله rahul mohanrao بند | rahul mohanrao band
department of forensic medicine and toxicology, lady hardinge medical college, new delhi, india


mahesh chand meena | mahesh chand meena
department of forensic medicine and toxicology, lady hardinge medical college, new delhi, india


alok kandpal | alok kandpal
department of forensic medicine and toxicology, lady hardinge medical college, new delhi, india


sachin mittal | sachin mittal
department of forensic medicine and toxicology, lady hardinge medical college, new delhi, india
نشانی اینترنتی http://apjmt.mums.ac.ir/article_4164.html
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