این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Asia Pacific Journal of Medical Toxicology، جلد ۳، شماره ۳، صفحات ۱۱۰-۱۱۴
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Spirometric Findings in TNT Factory Workers Compared with Unexposed Controls
چکیده انگلیسی مقاله Background: Trinitrotoluene (TNT) is one of the most well-known and oldest explosive agents. In the recent decade, bioenvironmental, biochemical, and biological effects of TNT exposure have been more in the spotlight. In this study, we aimed to evaluate spirometric parameters in workers of a TNT factory exposed to TNT and other related fumes and dusts compared with the unexposed controls. Methods: In this case-control study, spirometry was done for TNT factory workers (cases) and matched healthy controls, and their results were compared with each other. Matched controls were selected from workers who worked in the same geographic area without any history of TNT or other chemical materials exposure. Spirometric studies were done during the early hours of day. Results: Overall, 90 subjects (47 TNT exposed cases and 43 controls) were included. The two groups showed no significant difference in demographic characteristics and smoking habits. In spirometry, it was found that the cases had significantly lower forced vital capacity (91.4 ± 13.7% vs. 100.2 ± 13.0%, P = 0.002), forced expiratory volume in 1 second (98.0 ± 14.9% vs. 104.7 ± 12.5%, P = 0.024) and peak expiratory flow (98.4 ± 17.3% vs. 107.9 ± 21.7%, P = 0.025) compared with controls. According to spirometric findings, 10 cases (21.3%) and no controls had restrictive pattern, which means TNT factory workers had 1.27 (CI: 1.09-1.47, P = 0.001) fold risk for development of restrictive patterns. Conclusion: Chronic exposure to TNT or prolonged working in TNT factories may predispose the workers to respiratory disorders. In addition to regular screening programs, preventive measures and devices should be considered for TNT factory workers to reduce the harms.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله مجید شهرتی | majid shohrati
chemical injuries research center, baqiyatallah university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی بقیه الله (Baqiyatallah university of medical sciences)

بیتا نجفیان | bita najafian
chemical injuries research center, baqiyatallah university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی بقیه الله (Baqiyatallah university of medical sciences)

امین صبوری | amin saburi
health research center, baqiyatallah university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی بقیه الله (Baqiyatallah university of medical sciences)

انسیه واحدی | ensiyeh vahedi
chemical injuries research center, baqiyatallah university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی بقیه الله (Baqiyatallah university of medical sciences)

مصطفی قانعی | mostafa ghanei
chemical injuries research center, baqiyatallah university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی بقیه الله (Baqiyatallah university of medical sciences)

نشانی اینترنتی http://apjmt.mums.ac.ir/article_3379.html
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده 1
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات