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Journal of Cardio-Thoracic Medicine، جلد ۲، شماره ۲، صفحات ۱۴۳-۱۴۶
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی A comparison of HTLV-1 Infection Frequency in Patients with or without Tuberculosis
چکیده انگلیسی مقاله Introduction: To recognize the predisposing factors in tuberculosis as an endemic infection in Northeast province of Iran, this study was aimed to evaluate whether HumanT-lymphocyte type 1 (HTLV-I) as an immunosuppressive factor increases the risk of tuberculosis. Materials and Methods: A Case-control study was conducted in 278 tuberculosis patients from 2007 to 2010, in Mashhad, Iran. Tuberculosis has been diagnosed by gold standard tests like sputum culture, bronchoalveolar lavage (BAL) culture or cytology. For detection of HTLV-I antibody, Enzyme Linked Immunosorbant Assay method and western Blot as the confirming test were performed. Then 276 healthy cases were matched for gender and age. Results: The mean age of tuberculosis patients was 49.67±21.36 years and for control cases was 48.36±20.74. In patients group, 114 (41.6%) were male, 160 (58.4%) were female and in controls 123 (44.6%) were male and 153 (55.4%) were female. Pulmonary tuberculosis was presented in 84.2% of the patients. The frequency of HTLV-1 was 2.9% and 3.3% in patients and controls, respectively.HTLV-I frequency was higher in male patients and it increased by age. Conclusion: Regarding to this study, HTLV-I infection is not stand-alone sufficient for increasing the risk of tuberculosis.
کلیدواژه‌های انگلیسی مقاله Case-Control, HTLV-1, Immunosuppression, Tuberculosis
نویسندگان مقاله لیلا ghofraniha | leila ghofraniha
pulmonologist, chronic obstructive pulmonary disease research center, faculty of medicine, mashhad university ofmedical sciences, mashhad, iran


الهام قلعه نوی | elham ghalenavi
internist, chronic obstructive pulmonary disease research center, faculty of medicine, mashhad university of medicalsciences, mashhad, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

داود عطاران | davood attaran
pulmonologist, cardio‐thoracic surgery amp; transplant research center, emam reza hospital, faculty of medicine,mashhad university of medical sciences, mashhad, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

محمد توحیدی | mohammad towhidi
pulmonologist, chronic obstructive pulmonary disease research center, faculty of medicine, mashhad university ofmedical sciences, mashhad, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

هوشنگ رفعت پناه | hooshang rafatpanah
immunologist, immunology research center, faculty of medicine, mashhad university of medical sciences, mashhad,iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

محمد khajehdaloee | mohamad khajehdaloee
community medicine specialist, faculty of medicine, mashhad university of medical sciences, mashhad, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

محمدرضا سروقد مقدم | mohamad reza sarvghad moghadam
infectious disease department, imam reza hospital, faculty of medicine, mashhad university of medical sciences,mashhad, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

نشانی اینترنتی http://jctm.mums.ac.ir/article_2608.html
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