این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Journal of Cardio-Thoracic Medicine، جلد ۲، شماره ۱، صفحات ۱۰۹-۱۱۲
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Overlap Syndrome in Respiratory Medicine: Asthma and Chronic Obstructive Pulmonary Disease
چکیده انگلیسی مقاله Asthma and chronic obstructive pulmonary disease (COPD) are highly prevalent chronic diseases in the general population. Both are characterized by similar mechanisms: airway inflammation, airway obstruction, and airway hyperresponsiveness. However, the distinction between the two obstructive diseases is not always clear. Multiple epidemiological studies demonstrate that in elderly people with obstructive airway disease, as many as half or more may have overlapping diagnoses of asthma and COPD. A COPD-Asthma overlap syndrome is defined as an airflow obstruction that is not completely reversible, accompanied by symptoms and signs of increased obstruction reversibility. For the clinical identification of overlap syndrome COPD-Asthma Spanish guidelines proposed six diagnostic criteria. The major criteria include very positive bronchodilator test [increase in forced expiratory volume in one second (FEV1) ≥15% and ≥400 ml], eosinophilia in sputum, and personal history of asthma. The minor criteria include high total IgE, personal history of atopy and positive bronchodilator test (increase in FEV1 ≥12% and ≥200 ml) on two or more occasions. The overlap syndrome COPD-Asthma is associated with enhanced response to inhaled corticosteroids due to the predominance of eosinophilic bronchial inflammation.The future clinical studies and multicenter clinical trials should lead to the investigation of disease mechanisms and simultaneous development of the novel treatment.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله آلکساندرا corlateanu | alexandru corlateanu
pulmonologist,department of respiratory medicine, state university of medicine and pharmacy amp;quot;nicolae testemitanu amp;quot;, chisinau,moldova, ers national delegate for moldova, gold national leader for moldova


valeria pripa | valeria pripa
pulmonologist,department of respiratory medicine, state university of medicine and pharmacy amp;quot;nicolae testemitanu amp;quot;, chisinau,moldova

سازمان اصلی تایید شده: 0 دانشگاه های خارج از کشور

گلوریا montanari | gloria montanari
pulmonologist,department of medical and surgical sciences for children amp; adults, university of modena and reggio emilia, modena,italy

سازمان اصلی تایید شده: 0 دانشگاه های خارج از کشور

ویکتور botnaru | victor botnaru
pulmonologist,department of respiratory medicine, state university of medicine and pharmacy amp;quot;nicolae testemitanu amp;quot;, chisinau,moldova

سازمان اصلی تایید شده: 0 دانشگاه های خارج از کشور

نشانی اینترنتی http://jctm.mums.ac.ir/article_2190.html
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده 3
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات