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Iranian Journal of Blood and Cancer، جلد ۱۰، شماره ۴، صفحات ۱۱۷-۱۲۳
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عنوان انگلیسی Risk Factors of Deep Vein Thrombosis in Cancer Patients
چکیده انگلیسی مقاله Background: Venous thromboembolism (VTE) is a significant complication in cancer patients which was found in 4-20% of the patients. This study was aimed to evaluate risk factors of deep vein thrombosis (DVT) in cancer patients in an oncology center in Indonesia.  Methods: This was a retrospective cohort study. Data were obtained from medical records of adult cancer patients with DVT referring to Dharmais National Cancer Center in Indonesia since 2013-2016. Control group were adult cancer patients without DVT. Association of risk factors (sex, age, presence of metastasis, Khorana score, complete blood count and D-dimer level) with DVT were compared and analyzed between DVT patients and control group. Results: A total of 129 cancer patients with DVT at Dharmais Cancer Hospital during year 2013-2016 met the inclusion criteria. Median age of the patients was 56 years old. Multivariate logistic regression analysis was performed to investigate the effect of sex, age, hypertension, diabetes, chemotherapeutic agents, hemoglobin level, leukocyte counts and D-dimer level to the occurrence of DVT in cancer patients. Hypertension (OR 16.7, P< 0.001), chemotherapy (OR 5.0, P=0.012), D-dimer level (OR 1.00, P=0.030) and leukocyte counts (OR 1.00, P=0.017) were significant risk factors to have contribution to the occurrence of DVT in cancer patients.  Conclusion: Hypertension, history of chemotherapy, leukocytosis, and D-dimer level were significant risk factors for DVT in cancer patients. 
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نویسندگان مقاله | Noorwati Sutandyo
Division of Hematology and Medical Oncology, Department of Internal Medicine, Dharmais National Cancer Centre Hospital – Jakarta


| Demak Tobing
Department of Clinical Pathology, Dharmais National Cancer Centre Hospital – Jakarta


| Kardinah Kardinah
Department of Radiology, Dharmais National Centre Hospital – Jakarta
نشانی اینترنتی http://ijbc.ir/browse.php?a_code=A-10-401-1&slc_lang=en&sid=1
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/98/article-98-1153630.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Adults Hematology & Oncology
نوع مقاله منتشر شده پژوهشی
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