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Journal of Pharmaceutical Care، جلد ۱، شماره ۱، صفحات ۸-۱۲

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عنوان انگلیسی The role of Clinical Pharmacists in the improvement of a pharmacovigilance system: A review of the reported adverse drug reactions during 2004-2010 in Mazandaran Province of Iran.
چکیده انگلیسی مقاله Background : Following establishment of Iranian Adverse Drug Reaction (ADR) Monitoring Center in 1997, ADR committees were established in all hospitals of Mazandaran Province of Iran. Clinical pharmacists from Mazandaran University of Medical Sciences have been involved with these committees since 2007. The aim of this study was to compare the results of the pharmacovigilance system before and after active involvement of clinical pharmacists. Methods : This study included Yellow Cards filled out by healthcare providers inMazandaran Province during 2004-2010. Frequency of Adverse Drug Reactions (ADRs), route of administration, reporters, number of reports in each years and damaged organs were focuses. Statistical analysis was performed by SPSS 16 software. P< 0.05 was considered as significant difference. Results : A total of 793 yellow cards were completed during 2004 – 2010. Only 38 ADRs(4.8%) were related to 2004-2007. Most of the reports generated by Nurses (49.3%) followed by Pharmacists and Physicians (P< 0.001). Forty-one reactions (5.2%) were serious, most related to Ceftriaxone, Desfonac and Vancomycin. Conclusion: Clinical pharmacists’ intervention regarding establishing ADR committees in the hospitals improved the output of the pharmacovigilance system, although under- reporting is still a major drawback of spontaneous reporting.
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نویسندگان مقاله ابراهیم صالحی فر | ebrahim salehifar
associate professor of clinical pharmacy, mazandaran university of medical sciences, faculty of pharmacy, clinical pharmacy department, pharmaceutical research center, pharmaceutical care department of emam khomeini hospital, sari, mazandaran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مازندران (Mazandaran university of medical sciences)

شهرام علا | shahram ala
associate professor of clinical pharmacy, mazandaran university of medical sciences, faculty of pharmacy, clinical pharmacy department, pharmaceutical research center, pharmaceutical care department of emam khomeini hospital, sari, mazandaran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مازندران (Mazandaran university of medical sciences)

مینا امینی | mina amini
pharmacist, pharmaceutical care department of emam khomeini hospital, sari, mazandaran, iran


الهام اژدری | elham azhdari
pharmacist, pharmaceutical care department of emam khomeini hospital, sari, mazandaran, iran


فرزانه میر شفا | farzaneh mir shafa
pharmacist, food and drug deputy of mazandaran university of medical sciences, sari, mazandaran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مازندران (Mazandaran university of medical sciences)


نشانی اینترنتی http://jpc.tums.ac.ir/index.php/jpc/article/view/3
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