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Middle East Journal of Digestive Diseases، جلد ۸، شماره ۱، صفحات ۵-۰
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عنوان انگلیسی Epidemiological Profile of Hepatitis B Virus Infection in Iran in the Past 25 years; A Systematic Review and Meta-analysis of General Population Studies
چکیده انگلیسی مقاله INTRODUCTION Chronic hepatitis B virus (HBV) infection is one of the most important health problems worldwide with a high rate of morbidity and mortality. It is a major risk factor for cirrhosis and liver cancer. Currently, Iran is located in the intermediate HBV zone; however, recent studies have provided some evidence indicating an epidemiological change in the country. The aim of this study was to estimate the prevalence of HBV in Iran. METHODS A systematic review was conducted to evaluate the studies performed in the past 25 years that have reported the prevalence of HBV infection and its associated factors in the Iranian general population (1990-2014). Any study assessing and reporting serum Hbs Ag levels was included in this review. RESULTS After excluding all impertinent studies, 19 eligible studies were included in the analysis. The overall prevalence of HBV was 3% (95% CI 2% to 3%). Its distribution showed that the prevalence of HBV varies in different provinces from 0.87% to 8.86%. The HBV rate was highest in the Golestan (8.86%) and lowest in the Kurdistan (0.87%) provinces. CONCLUSION This study provides some evidence about the prevalence of HBV in Iran. However, the collected data was very heterogenic, even within a single province, which made it hard to estimate a single-point prevalence. High quality studies are needed to find reliable information about HBV prevalence and to decrease the heterogeneity of results in the country.
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نویسندگان مقاله زهرا محمدی | zahra mohammadi


عباسعلی کشتکار | abbasali keshtkar


ساره اقتصاد | sareh eghtesad


علیرضا jeddian | alireza jeddian


علی اکبر پورفتح اله | ali akbar pourfatholah


مهتاب مقصودلو | mahtab maghsudlu


مریم زادسر | maryam zadsar


زهرا محمودی | zahra mahmoudi


آمنه shayanrad | amaneh shayanrad


حسین پوستچی | hossein poustchi


رضا ملک زاده | reza malekzadeh


نشانی اینترنتی http://www.mejdd.org/index.php/mejdd/article/view/1582
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Systematic Review
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