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Middle East Journal of Digestive Diseases، جلد ۴، شماره ۴، صفحات ۲۲۴-۰
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عنوان انگلیسی Treatment of Gastro-Esophageal Reflux Disease May improve Surgical Outcomes for Chronic Otitis Media
چکیده انگلیسی مقاله BACKGROUND This study has been designed to investigate the clinical association between gastro esophageal reflux disease (GERD) and chronic otitis media (COM) in adults and also the role of GERD treatment on the outcome of COM surgery. METHODS In a randomized clinical trial, 58 patients with COM who were candidates for surgery were evaluated for GERD and divided in two groups; GERD posi­tive (case) and GERD negative (control) patients. The GERD positive patients were randomized to either receiving medical treatment for GERD or not prior to surgery. The surgical outcomes were assessed at 3 and 6 months after COM surgery in the three groups. RESULTS Fifty-eight (26 males) patients were enrolled. Forty-two (72.4%) of these had GERD according to a validated questionnaire. Three months after surgery auditory recovery in GERD negative patients was significantly higher [16(100%)] than those suffering from GERD [28 out of 42 (66.7%)], p =0.008. The figures remained similar at six months follow up as well (100 % vs. 72.5% in GERD negative and positive patients respectively, p =0.002). In the GERD-positive group, 8 of 18 (44.4%) patients who did not receive GERD treatment before tympanomastoidectomy recovered after three months whereas, while 20 of 24 (83.3%) patients who received GERD treatment recovered during this time ( p˂ 0.001). At six months 44.4% of non-treated GERD patients had auditory recovery as compared to 95.5 % of those treated for GERD ( p˂ 0.01). CONCLUSION Our data show that the effect of GERD on the outcome of COM surgery may be considerable. On the other hand, treating COM patients for GERD medi­cally for two months before tympanoplasty improves the surgical outcomes. Therefore, we suggest that COM patients be evaluated for GERD before un­dergoing tympanoplasty and if GERD is present, they be treated medically for a couple of months before undergoing surgery.
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نویسندگان مقاله علیرضا ملک زاده | alireza malekzadeh


اردوان تاجدینی | ardavan tajdini


رضا ملک زاده | reza malekzadeh


سیاوش ناصری مقدم | siavosh nasseri moghaddam


مریم مظلوم | maryam mazlum


حبیبه نخبه زعیم | habibeh nokhbeh zaeem


پرستو بی آزار | parastoo biazar


ماندانا امیری | mandana amiri


نشانی اینترنتی http://www.mejdd.org/index.php/mejdd/article/view/1041
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نوع مقاله منتشر شده Original Article
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