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Middle East Journal of Digestive Diseases، جلد ۳، شماره ۲، صفحات ۹۲-۰
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Hepatitis B Virus Infection during Pregnancy: Transmission and Prevention
چکیده انگلیسی مقاله A Hepatitis B virus (HBV) infection is a global public health problem. In endemic areas, HBV infection occurs mainly during infancy and early childhood, with mother to child transmission (MTCT) accounting for approximately half of the transmission routes of chronic HBV infections. Prevention of MTCT is an essential step in reducing the global burden of chronic HBV. Natal transmission accounts for most of MTCT, and providing immunoprophylaxis to newborns is an excellent way to block natal transmission. Prenatal transmission is responsible for the minority of MTCT not preventable by immunoprophylaxis. Be­cause of the correlation between prenatal transmission and the level of maternal viremia, some authors find it sound to offer lamivudine in women who have a high viral load (more than 8 to 9 log 10 copies/mL). In addition to considerations regarding the transmission of HBV to the child, the combination of HBV infection and pregnancy raises several unique management issues. Chronic HBV infection during pregnancy is usually mild but may flare after delivery or with discontinuing thera­py. Management of chronic HBV infection in pregnancy is mostly sup­portive with antiviral medications indicated in a small subset of HBV infected women with rapidly progressive chronic liver disease.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله بهروز نوابخش | behrouz navabakhsh


نرگس محرابی | narges mehrabi


آرزو استخری | arezo estakhri


مهدی محمدنژاد | mehdi mohamadnejad


حسین پوستچی | hossein poustchi


نشانی اینترنتی http://www.mejdd.org/index.php/mejdd/article/view/392
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Review Article
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