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Middle East Journal of Digestive Diseases، جلد ۳، شماره ۱، صفحات ۵-۰

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عنوان انگلیسی Epidemiology of Celiac Disease in Iran: A Review
چکیده انگلیسی مقاله   Celiac disease (CD) was traditionally believed to be a chronic enteropathy, almost exclusively affecting people of European origin. Celiac disease is the permanent intolerance to dietary gluten, the major protein component of wheat. The availability of new, simple, very sensitive and specific serological tests has shown that CD is as common in Middle Eastern countries as in Europe, Australia and New Zealand where the major dietary staple is wheat. A high prevalence of CD has been found in Iran, in both the general population and the at-risk groups, i.e. patients with type 1 diabetes or irritable bowel syndrome (IBS). In developing countries, serological testing in at risk groups is necessary for early identification of celiac patients. Clinical studies show that presentation with non-specific symptoms or a lack of symptoms is as common in the Middle East as in Europe. Wheat is a major component of the Iranian diet and exposure to wheat proteins induces some degree of immune tolerance, lead­ing to milder symptoms that may be mistaken with other GI dis­orders. The implementation of gluten free diet (GFD) is a major challenge for both patients and clinicians in Iran, especially since commercial gluten-free products are not available in this area.
کلیدواژه‌های انگلیسی مقاله Celiac disease,Epidemiology,Iran

نویسندگان مقاله m رستمی نژاد | m rostami nejad


کامران رستمی | kamran rostami


محمد حسن امامی | mohammad hassan emami


دکتر محمدرضا زالی | mohammad reza zali


رضا ملک زاده | reza malekzadeh



نشانی اینترنتی http://www.mejdd.org/index.php/mejdd/article/view/169
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Review Article
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