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Research Journal of Pharmacognosy، جلد ۱، شماره ۱، صفحات ۲۳-۲۶
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عنوان انگلیسی Identification of amino acids in Securigera securidaca, a popular medicinal herb in Iranian folk medicine
چکیده انگلیسی مقاله Securigera securidaca (L.) Degen & Dorfl grows in different parts of Iran. The seeds of the species are used in Iranian folk medicine as an anti-diabetic agent. Many studies have established hypoglycemic effects of amino acids and in the present investigation, amino acids of Securigera securidaca seeds have been evaluated. The ground seeds were extracted using petroleum ether, hot ethanol and ethanol 50%, respectively. ethanol 50% extract was chromatographed over cation exchanging resin and the resulting amino acid fraction was subjected to HPLC after OPA derivatization and the amino acids were identified by comparing to standards. The results evidenced the presence of 19 amino acids in the plant extract including alanine, arginine, asparagine, aspartic acid, citrulline, glutamic acid, glutamine, glycine, histidine, isoleucine, leucine, lysine, methionine, phenylalanine, serine, threonine, tyrosine and valine. Considering the role of some amino acids in diabetes the above amino acids could be noted as hypoglycemic agents of the plant seeds but further studies are necessary.
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نویسندگان مقاله سیدابراهیم سادات ابراهیمی | s e sadat ebrahimi
department of medicinal chemistry, faculty of pharmacy, tehran university of medical sciences, tehran, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

m حسن پور میر | hassanpoor mir
pharmaceutical sciences branch, islamic azad university, tehran, iran.
سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)

غلامرضا امین | g r
department of pharmacognosy, faculty of pharmacy, tehran university of medical sciences, tehran, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

h حاجی مهدی پور |
department of traditional pharmacy, school of traditional medicine, shahid beheshti university of medical sciences, tehran, iran. traditional medicine and materia medica research center, shahid beheshti university of medical sciences, tehran, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)

نشانی اینترنتی http://www.rjpharmacognosy.ir/article_3905_bbac27d5aca927737db112abc9190b3a.pdf
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