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Archives of Anesthesiology and Critical Care، جلد ۱، شماره ۲، صفحات ۴۲-۴۵
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عنوان انگلیسی Comparison of Analgesic Effects of B Vitamins and Diclofenac plus B Vitamins During General Anesthesia and PACU
چکیده انگلیسی مقاله Background: B Vitamins deficiencies in humans and animals have been known for some time to induce pain and inflammation. These symptoms can be readily alleviated by appropriate administration of Vitamins B. The aim of this study was to evaluate opioids requirements and hemodynamic variables and analgesic effect of B Vitamins and B Vitamins-diclofenac in general anesthesia and Post-anesthesia care unit (PACU). Methods: In this randomized prospective and double-blinded clinical trial study 105 patients undergoing orthopedic surgery were assessed. Patients were then randomized to receive placebo, B vitamin and diclofenac plus B Vitamins. Preinduction and postinduction hemodynamic parameters and opioid requirement were measured. Results: Sufentanil requirement postoperatively was significantly lower in the DB group (0.12 µg/kg) and B group (0.17 µg/kg) compared with the Placebo group (0.2 µg/kg) (P=0.001). Maximum mean systolic blood pressure related to basal heart rate were increased in DB group 20±6%, B group 30± 17% and P group 35± 9% with significant difference in three groups (P= 0.0001). Discussion: Analgesic effect of diclofenac plus B Vitamins was better than B Vitamins and required less opioid agents.
کلیدواژه‌های انگلیسی مقاله B vitamins,diclofenac,general anesthesia,analgesia
نویسندگان مقاله عباس استاد علیپور | abbas ostad alipour
department of anesthesiology and critical care, farabi hospital, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

مصطفی صادقی | mostafa sadeghi
department of anesthesiology and critical care, shariati hospital, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

زاهد حسین خان | zahid hussain khan
department of anesthesiology and critical care, imam khomeini medical center, tehran university medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه تهران (Tehran university)

مریم جمشیدی | maryam jamshidi
department of anesthesiology and critical care, tehran university medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه تهران (Tehran university)

جلیل مکارم | jalil makarem
department of anesthesiology and critical care, imam khomeini medical center, tehran university medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه تهران (Tehran university)

امیر عباس یاقوتی | amir abbas yaghooti
department of anesthesiology and critical care, bahrami hospital, tehran university medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه تهران (Tehran university)

نشانی اینترنتی http://aacc.tums.ac.ir/index.php/aacc/article/view/11
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زبان مقاله منتشر شده en
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