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Iranian Journal of Biotechnology، جلد ۱۴، شماره ۳، صفحات ۷۰-۸۱
عنوان فارسی
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عنوان انگلیسی Role of Nanodiamonds in Drug Delivery and Stem Cell Therapy
چکیده انگلیسی مقاله Context: The use of nanotechnology in medicine and more specifically drug delivery is set to spread rapidly. Currently many substances are under investigation for drug delivery and more specifically for cancer therapy. Evidence Acquisition: Nanodiamonds (NDs) have contributed significantly in the development of highly efficient and successful drug delivery systems, and in stem cell therapy. Drug delivery through NDs is an intricate and complex process that deserves special attention to unravel underlying molecular mechanisms in order to overcome certain bottlenecks associated with it. It has already been established that NDs based drug delivery systems have excellent biocompatibility, non-toxicity, photostability and facile surface functionalization properties. Results: There is mounting evidence that suggests that such conjugated delivery systems well retain the properties of nanoparticles like small size, large surface area to volume ratio that provide greater biocatalytic activity to the attached drug in terms of selectivity, loading and stability. Conclusions: NDs based drug delivery systems may form the basis for the development of effective novel drug delivery vehicles with salient features that may facilitate their utility in fluorescence imaging, target specificity and sustained-release.
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نویسندگان مقاله shakeel احمد انصاری | shakeel ahmed
center of excellence in genomic medicine research, king abdulaziz university, jeddah

rukhsana ستار |
department of biochemistry, ibn sina national college for medical sciences, jeddah-21418, kingdom of saudi arabia

محمد عالم جعفری | mohammad alam
center of excellence in genomic medicine research, king abdulaziz university, jeddah-21589, kingdom of saudi arabia

محمود رسول |
center of excellence in genomic medicine research, king abdulaziz university, jeddah-21589, kingdom of saudi arabia

waseem احمد |
center of excellence in genomic medicine research, king abdulaziz university, jeddah-21589, kingdom of saudi arabia

سید kashif زیدی | syed kashif
center of excellence in genomic medicine research, king abdulaziz university, jeddah-21589, kingdom of saudi arabia

نشانی اینترنتی http://www.ijbiotech.com/article_15456_f38ee4331e950d147ad19918fe9a9a15.pdf
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