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Iranian Journal of Biotechnology، جلد ۱۴، شماره ۲، صفحات ۵۸-۶۲
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عنوان انگلیسی Phylogenetic Analysis of Aedes aegypti Based on Mitochondrial ND4 Gene Sequences in Almadinah, Saudi Arabia
چکیده انگلیسی مقاله Background: Aedes aegypti is the main vector of the yellow fever and dengue virus. This mosquito has become the major indirect cause of morbidity and mortality of the human worldwide. Dengue virus activity has been reported recently in the western areas of Saudi Arabia. There is no vaccine for dengue virus until now, and the control of the disease depends on the control of the vector. Objectives: The present study has aimed to perform phylogenetic analysis of Aedes aegypti based on mitochondrial NADH dehydrogenase subunit 4 (ND4) gene at Almadinah, Saudi Arabia in order to get further insight into the epidemiology and transmission of this vector. Materials and Methods: Mitochondrial ND4 gene was sequenced in the eight isolated Aedes aegypti mosquitoes from Almadinah, Saudi Arabia, sequences were aligned, and phylogenetic analysis were performed and compared with 54 sequences of Aedes reported in the previous studies from Mexico, Thailand, Brazil, and Africa. Results: Our results suggest that increased gene flow among Aedes aegypti populations occurs between Africa and Saudi Arabia. Conclusions: Phylogenetic relationship analysis showed two genetically distinct Aedes aegypti in Saudi Arabia derived from dual African ancestor.
کلیدواژه‌های انگلیسی مقاله Aedes,Mosquito,ND4 gene,Phylogenetic,Saudi Arabia
نویسندگان مقاله خلیل h آل علی | khalil h al ali
department of medical laboratory technology, college of applied medical sciences, taibah university, almadinah almanwra, kingdom of saudi arabic

آیمان a el بدری | ayman a el badry
department of medical parasitology, kasr al-ainy school of medicine, cairo university, cairo, egypt

mouhanad آل علی | al ali
department of institut supérieur de la santé et des bioproduits d’angers, université d’angers, angers, france

wael s m el سید | wael s m el sayed
department of microbiology, faculty of science, ain shams university, cairo 11566, egypt department of biology, faculty of science, taibah university, almadinah almunawarah 344, saudi arabia

هشام a el beshbishy | hesham a el beshbishy
department of medical laboratory technology, college of applied medical sciences, taibah university, almadinah almanwra, kingdom of saudi arabic department of biochemistry, faculty of pharmacy, al-azhar university, nasr city, cairo, egypt

نشانی اینترنتی http://www.ijbiotech.com/article_14134_c352342aadcaab1564b8d833431517dd.pdf
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