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Iranian Journal of Biotechnology، جلد ۱۳، شماره ۴، صفحات ۳۸-۴۲
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عنوان انگلیسی Evaluation of Antifungal Effect of Silver Nanoparticles Against Microsporum canis, Trichophyton mentagrophytes and Microsporum gypseum
چکیده انگلیسی مقاله Background : Dermatophytosis is the common cutaneous infections in humans and animals, which is caused by the keratinophylic fungus called dermatophytes. In recent years , drug-resistance in pathogenic fungi, including dermatophytes to the current antifungal have been increased . The aim of this study was to evaluate the antifungal efficacy of AgNPs against Microsporum canis, Trichophyton mentagrophytes, and Microsporum gypseum. Materials and Methods: The antifungal susceptibility of nano-silver particles (AgNPs) compared with Griseofulvin (GR). Its efficacy was investigated against three strains of dermatophytes by both agar dilution and broth microdilution test (BMD). Results : The average minimum inhibitory concentration (MIC) of Ag-NPs on M. canis, T. mentagrophytes and M. gypseum were 200, 180, and 170 μg/ml , respectively. Whereas these strains showed MIC of 25, 100 and 50 μg/ml for Griseofulvin (GR). Conclusions: Our finding indicated that the AgNPs was less active than Griseofulvin (GR) but it had anti-dermatophytic effect.
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نویسندگان مقاله سید امین آیت اللهی موسوی | seyyed amin ayatollahi mousavi
department of medical mycology and parasitology, school of medicine, medical university of kerman, kerman, iran. research center for tropical and infectious diseases, kerman university of medical sciences, kerman, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمان (Kerman university of medical sciences)

سمیرا سالاری |
department of medical mycology and parasitology, school of medicine, medical university of kerman, kerman, iran. research center for tropical and infectious diseases, kerman university of medical sciences, kerman, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمان (Kerman university of medical sciences)

ساناز هادی زاده |
department of medical mycology and parasitology, school of medicine, medical university of kerman, kerman, iran

نشانی اینترنتی http://www.ijbiotech.com/article_11913_dcf4eacb3434d04fe49cb38e326091a6.pdf
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