این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Iranian Journal of Public Health، جلد ۴۶، شماره ۵، صفحات ۶۲۶-۶۳۳
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Comparative Evaluation of Heavy Metals in Patients with Rheumatoid Arthritis and Healthy Control in Pakistani Population
چکیده انگلیسی مقاله Background: Exposure to heavy metals in development of many diseases has been investigated previously, specially created by oxidative stress. The etiology of Rheumatoid arthritis (RA) is still not fully understood but oxidative stress created by heavy metals may have role in development of RA. The aim of present study was to compare serum level of heavy metals in RA and healthy control individuals. Methods: Blood samples of 100 RA patients were collected from different hospitals in district Sargodha, Punjab, Pakistan and 100 control individuals from Dec 2013 to May 2014.The serum samples were analyzed for determination of Pb, Cd, Cr and Ni through Atomic absorption spectrophotometer (AA 6600 Shimadzu). Results: Statistically highly significant difference was observed between RA patients and healthy control individuals for Pb, Cd, Cr, and Ni level (P< 0.01). The difference between the means of both sexes was not significant for Pb and Cd concentrations (P>0.01). For Cr the difference between the means of both sexes was statistically not significant in RA +ve patients and highly significant difference was observed between both sexes in healthy control group (P< 0.01). The difference between the means of both sexes for Ni was statistically non-significant in healthy control group while significant difference was observed between both sexes in RA +ve group (P< 0.05). Statistically non-significant difference for Pb, Cd, Cr and Ni level was found among the all three age groups of RA and healthy control individuals (P>0.01). Conclusion: Concentration of heavy metals in serum samples of RA patients and healthy control individuals differ significantly, which shows that heavy metals may contributes towards development of RA.   Keywords: Rheumatoid arthritis, Heavy metals, Serum, Pakistan  
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله | Shazia IRFAN
Dept. of Zoology, University of Sargodha, Sargodha, Pakistan


| Asima RANI
Dept. of Zoology, University of Sargodha, Sargodha, Pakistan


| Naila RIAZ
Dept. of Zoology, University of Sargodha, Sargodha, Pakistan


| Muhammad ARSHAD
Principal, University of Education, Lower Mall Campus, Lahore, Pakistan


| Syed KASHIF NAWAZ
Dept. of Zoology, University of Sargodha, Sargodha, Pakistan
نشانی اینترنتی http://ijph.tums.ac.ir/index.php/ijph/article/view/9911
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/86/article-86-1354316.pdf
کد مقاله (doi)
زبان مقاله منتشر شده
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات