| چکیده انگلیسی مقاله |
Background: The extremely low-frequency electromagnetic field (ELF-EMF), mainly emitted by electric transmission lines and household electronic appliances, is becoming a worldwide health risk. It is imperative to investigate the biological impacts of ELF-EMF and to identify products that are resistant to the radiation from 50 Hz ELF-EMF. In this study, we investigated the biological impacts of apoptosis caused by 50 Hz Power line ELF-EMF and the protective effects of Vit C and Vit E. Methods: We conducted this study in Beijing, China in 2013. B95-8 and Balb/c-3T3 cells were divided into a sham group, an expo group and 3 expo groups in which the cells were preincubated with various concentrations of Vit C and Vit E. Then, all of the cells were exposed to 50 Hz Power line ELF-EMF and examined for apoptosis. The cells were collected for apoptosis detection after exposure. Results: The percent of cells that undergoing apoptosis and preincubated with various concentrations of Vit C and Vit E were significantly lower than in the Expo group. Conclusion: Vit C and Vit E exert significant protective effects from 50 Hz ELF-EMF radiation. The optimal protective concentrations of Vit C and Vit E are 10 μmol/L and 25 μmol/L, respectively. The protective effect of vitamins was more apparent for Balb/c-3T3 cells than B95-8 cells. |
| نویسندگان مقاله |
| Zhen DING
Beijing Key Laboratory of Environmental and Viral Oncology, School of Life Science and Bio-Engineering, Beijing University of Technology, Beijing, 100124, China
| Jintao LI
Beijing Key Laboratory of Environmental and Viral Oncology, School of Life Science and Bio-Engineering, Beijing University of Technology, Beijing, 100124, China State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, 100052, China
| Fan LI
Beijing Key Laboratory of Environmental and Viral Oncology, School of Life Science and Bio-Engineering, Beijing University of Technology, Beijing, 100124, China
State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, 100052, China
| Mohammadreza Mohammadzad MEPHRYAR
Beijing Key Laboratory of Environmental and Viral Oncology, School of Life Science and Bio-Engineering, Beijing University of Technology, Beijing, 100124, China
State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, 100052, China
| Shuicai WU
Beijing Key Laboratory of Environmental and Viral Oncology, School of Life Science and Bio-Engineering, Beijing University of Technology, Beijing, 100124, China
| Chen ZHANG
China Academy of Telecommunication Research of Ministry of Industry and Information Technology, Beijing, 100191, China
| Yi ZENG
Beijing Key Laboratory of Environmental and Viral Oncology, School of Life Science and Bio-Engineering, Beijing University of Technology, Beijing, 100124, China
State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, 100052, China
|