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Veterinary Research Forum، جلد ۶، شماره ۱، صفحات ۲۳-۲۹
عنوان فارسی
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عنوان انگلیسی The histological and histometrical effects of Urtica dioica extract on rat’s prostate hyperplasia
چکیده انگلیسی مقاله Benign prostatic hyperplasia (BPH) is a common disease in human that gradual overgrowth of the prostate gland leads to impinge on the urethra with impairment in urinary function. Numerous plants improve uncontrolled growth of the prostate gland and improve urinary tract symptoms associated with BPH. In this study, 25 healthy adult male Wistar rats were divided randomly in five groups: G1 (Control group) received ordinary feed without any treatment, G2 received 10 mg kg-1 testosterone subcutaneously, G3 received 50 mg kg-1 nettle root extract orally, G4 received 50 mg kg-1 nettle root extract orally and 10 mg kg-1 testosterone, G5 received 10 mg kg-1 almond oil (Almond oil was used as testosterone solvent) subcutaneously. After six weeks, volume and weight of each lobe were measured and samples were taken. The 5 to 6 µm thickness sections were made using paraffin embedding method and stained by hematoxylin and eosin and periodic acid-Schiff. The results showed that prostate volume and ratio of prostate to body weight were increased significantly in the testosterone. Histological and histometrical results showed that dorsal and lateral type 1 and 2 lobes were not changed significantly but the ventral and anterior lobes have changed significantly. Over all, the nettle root could prevent from some of prostatic hyperplasia effects, so that percentage of folded alveoli in ventral lobe reduced insignificantly.
کلیدواژه‌های انگلیسی مقاله Histometry,Hyperplasia,Prostate,Rat,Urtica dioica
نویسندگان مقاله حمیدرضا مرادی | hamid reza
department of basic sciences, faculty of veterinary medicine, shahid chamran university of ahvaz, ahvaz, iran
سازمان اصلی تایید شده: دانشگاه شهید چمران (Shahid chamran university)

نعیم عرفانی مجد | erfani majd
department of basic sciences, faculty of veterinary medicine, shahid chamran university of ahvaz, ahvaz, iran
سازمان اصلی تایید شده: دانشگاه شهید چمران (Shahid chamran university)

صالح اسماعیل زاده |
department of pathobiology, faculty of veterinary medicine, shahid chamran university of ahvaz, ahvaz, iran
سازمان اصلی تایید شده: دانشگاه شهید چمران (Shahid chamran university)

سید رضا فاطمی طباطبایی | sayed reza fatemi tabatabaei
department of basic sciences, faculty of veterinary medicine, shahid chamran university of ahvaz, ahvaz, iran
سازمان اصلی تایید شده: دانشگاه شهید چمران (Shahid chamran university)

نشانی اینترنتی http://vrf.iranjournals.ir/article_12180_7e564e91c52bf4839375aed930bb41a3.pdf
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