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Iranian Heart Journal، جلد ۲۰، شماره ۱، صفحات ۳۲-۳۸
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عنوان انگلیسی Impact of the Anatomical Factors of the Left Anterior Descending Coronary Artery in Patients With Single-Vessel Disease
چکیده انگلیسی مقاله Background: Despite the recognition of the common risk factors for coronary artery disease (CAD), itappears that there is a wider range of risk factors. The purpose of the present study was toevaluate the association between the anatomical factors and the increased risk of CADoccurrence and its clinical consequences.Methods: in this study, 50 cases with a single coronary artery stenosis of the left anterior descendingartery (LAD) and 50 controls with a normal coronary angiography or non-obstructive CADwere enrolled, and the objective of the study was compared between the 2 groups.Results: The number of the branches before the LAD stenosis significantly increased in the patientswith LAD disease, and there was a meaningful increase in the number of both the diagonal andseptal branches originating before the stenosis (P< 0.001). The average number of the diagonalbranches was the same in both groups, which was statistically insignificant. (P=0.986) Themean value of the angle between the largest diagonal branch or septal branch and the LAD inthe cases with CAD and the controls showed no significant difference. A family history of theearly-onset cardiovascular disease in the control group with non-obstructive CAD was 6%versus 20% in the CAD group, and this difference was statistically significant (P≤0.03).Conclusions: According to our study, it appears that the sum of the septal and diagonal branches of theLAD can be a statistically significant risk factor for the progression of atherosclerosis in theLAD as well. The LAD involvement is significantly associated with the familial type of CAD
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نویسندگان مقاله Amir Hossein Yazdi |
Department of Cardiology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, IR Iran

Ehsan Khalilipur |
Department of Cardiology, Birjand University of Medical Sciences, Birjand, IR Iran

Behshad Naghshtabrizi |
Department of Cardiology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, IR Iran

Mohammad Khaled Naghshbandi |
Department of Cardiology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, IR Iran

Farzaneh Esna-Ashari |
Department of Epidemiology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, IR Iran

نشانی اینترنتی http://journal.iha.org.ir/article_82790_e5601e54eadf66a4ea1d63004076acf5.pdf
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/162/article-162-1423844.pdf
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