این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Iranian Heart Journal، جلد ۱۹، شماره ۴، صفحات ۱۸-۲۵
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Heparin Initiation Before and After Femoral Arterial Access in Primary Percutaneous Coronary Intervention: Side Effects and Angiographic Success Rates
چکیده انگلیسی مقاله Background: Percutaneous coronary intervention (PCI) with the addition of potent antithrombotic medications is the best therapy recommended for ST-elevation myocardial infarction (STEMI). The prehospital administration of heparin is commonly prescribed in the absence of conclusive data supporting its administration time. We aimed to study the side effects of heparin administration, especially hematoma formation at the arterial access site, between patients who received it before and after femoral arterial access in PCI. Methods: This prospectively randomized clinical trial studied 128 patients who were diagnosed with STEMI and candidated for primary PCI at Rajaie Cardiovascular, Medical, and Research Center. Ninety-six patients who fulfilled the inclusion criteria were enrolled and randomly allocated to 2 groups according to a random table. The first group received heparin before the establishment of the femoral arterial access in the catheterization laboratory or in the ambulance (as soon as possible), while the second group received intravenous heparin after arterial access ion for primary PCI. The systemic side effects of heparin and its angiographic appearances were compared between the 2 groups. Results: The administration of unfractionated heparin before femoral arterial access in primary PCI had no more hematoma formation than did heparin injection after femoral arterial access (P=0.03). The study was unable to make any judgments regarding the angiographic thrombus burden before primary PCI according to the time of heparin injection because of the low volume of the patients; nonetheless, there was no significant difference between the 2 groups concerning thrombus burden. Conclusions: Heparin therapy before femoral arterial access in primary PCI had no deleterious effect on hematoma formation. (Iranian Heart Journal 2018; 19(4): 18-25)
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله Ali Zahed Mehr |
Cardiovascular Intervention Research Center, Rajaie Cardiovascular, Medical, and Research Center, Iran University of Medical Sciences, Tehran, IR Iran

Hamid Reza Sanati |
Cardiovascular Intervention Research Center, Rajaie Cardiovascular, Medical, and Research Center, Iran University of Medical Sciences, Tehran, IR Iran

Farshad Shakerian |
Cardiovascular Intervention Research Center, Rajaie Cardiovascular, Medical, and Research Center, Iran University of Medical Sciences, Tehran, IR Iran

Ata Firouzi |
Cardiovascular Intervention Research Center, Rajaie Cardiovascular, Medical, and Research Center, Iran University of Medical Sciences, Tehran, IR Iran

Reza Kiani |
Cardiovascular Intervention Research Center, Rajaie Cardiovascular, Medical, and Research Center, Iran University of Medical Sciences, Tehran, IR Iran

Mohammad Ali Zameni |
Rajaie Cardiovascular, Medical, and Research Center, Iran University of Medical Sciences, Tehran, IR Iran.

نشانی اینترنتی http://journal.iha.org.ir/article_83051_dcdba19f0320d7246fc3ff8f241119dc.pdf
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/162/article-162-1423853.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات